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      Nonunion of the femoral diaphysis : THE INFLUENCE OF REAMING AND NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

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          Abstract

          We assessed factors which may affect union in 32 patients with nonunion of a fracture of the diaphysis of the femur and 67 comparable patients whose fracture had united. These included gender, age, smoking habit, the use of non-steroidal anti-inflammatory drugs (NSAIDs) the type of fracture (AO classification), soft-tissue injury (open or closed), the type of nail, the mode of locking, reaming nu non-reaming, infection, failure of the implant, distraction at the fracture site, and the time to full weight-bearing. Patients with severe head injuries were excluded. Both groups were comparable with regard to gender, Injury Severity Score and soft-tissue injury. There was no relationship between the rate of union and the type of implant, mode of locking, reaming, distraction or smoking. There were fewer cases of nonunion in more comminuted fractures (type C) and in patients who were able to bear weight early. There was a marked association between nonunion and the use of NSAIDs after injury (p = 0.000001) and delayed healing was noted in patients who took NSAIDs and whose fractures had united.

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          Author and article information

          Journal
          The Journal of Bone and Joint Surgery. British volume
          The Journal of Bone and Joint Surgery. British volume
          British Editorial Society of Bone & Joint Surgery
          0301-620X
          2044-5377
          July 2000
          July 2000
          : 82-B
          : 5
          : 655-658
          Article
          10.1302/0301-620X.82B5.0820655
          10963160
          © 2000

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