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      Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.

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          Abstract

          We investigated proinflammatory M1 and immunomodulatory M2 activation profiles of circulating monocytes in relapsing experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis, and tested whether altered M1/M2 equilibrium promotes CNS inflammation.

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          Author and article information

          Journal
          Mult Scler
          Multiple sclerosis (Houndmills, Basingstoke, England)
          SAGE Publications
          1477-0970
          1352-4585
          Jan 2011
          : 17
          : 1
          Affiliations
          [1 ] University Victor Segalen, France.
          Article
          1352458510379243
          10.1177/1352458510379243
          20813772
          cb794c75-6fbd-446a-9e2f-8ca50a4f8e7b
          History

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