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      The Influence of Inflammation on the 125I-Fibrinogen Uptake Test in Experimental Thrombosis

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          Abstract

          The <sup>125</sup>I-fibrinogen uptake test was used in rabbits after the production of thrombosis in the marginal ear vein. The uptake was very similar with thrombosis produced by irritants, thrombin as well as with inflammation without thrombosis. The <sup>131</sup>I-albumin accumulated under these conditions to the same exten or even more than <sup>125</sup>I-fibrinogen. The local increase of permeability seemed to represent the most important factor in the uptake of both <sup>125</sup>I-fibrinogen und <sup>131</sup>I-albumin.

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          Author and article information

          Journal
          Journal ID (publisher-id): JVR
          Journal ID (nlm-ta): J Vasc Res
          Journal ID (doi): 10.1159/issn.1018-1172
          Title: Journal of Vascular Research
          Publisher: S. Karger AG
          ISSN (Print): 1018-1172
          ISSN (Electronic): 1423-0135
          Publication date Subscription-year: 1973
          Publication date (Print): 1973
          Publication date (Electronic): 18 September 2008
          Volume: 10
          Issue: 2
          Pages: 93-100
          Affiliations
          Research Centre of Cardiovascular Diseases (Head: Prof. L. Hejhal) of the Institute for Clinical and Experimental Medicine (Director: Prof. P. Málek), Prague
          Article
          Publisher ID: 157963 Other ID: Angiologica 1973;10:93–100
          DOI: 10.1159/000157963
          SO-VID: cb958a52-e325-4ff0-bf37-0e68a77b748c
          Copyright © © 1973 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 8
          Categories
          Subject: Paper

          ScienceOpen disciplines: General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Keywords: 125I-Fibrinogen uptake test,Inflammation,Experimental venous thrombosis
          Data availability:
          ScienceOpen disciplines: General medicine, Neurology, Cardiovascular Medicine, Internal medicine, Nephrology
          Keywords: 125I-Fibrinogen uptake test, Inflammation, Experimental venous thrombosis

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