Renal Amyloidosis Presenting as Water Losing Syndrome

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Abstract

In two patients with polyuria and polydipsia, renal biopsy revealed amyloidosis. Renal function studies showed specific disturbance of water conservation, with relatively intact diluting, acidifying and ammonium excreting capacity. In addition, the second patient had a nephrotic episode which completely disappeared within some months. It is suggested that the observed abnormalities result from selective impairment of water back-diffusion from the collecting ducts, in the presence of a relatively intact glomerular filtration.

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Journal

Journal ID (publisher-id): NEF

Journal ID (nlm-ta): Nephron

Journal ID (doi): 10.1159/issn.1660-8151

Title: Nephron

Publisher: S. Karger AG

ISSN (Print): 1660-8151

ISSN (Electronic): 2235-3186

Publication date Subscription-year: 1968

Publication date (Print): 1968

Publication date (Electronic): 26 November 2008

Volume: 5

Issue: 2

Pages: 81-89

Affiliations

Renal Division, Department of Medicine, University of Utrecht (Head: Prof. Dr. L.A. Hulst and Prof. Dr. F. L.J. Jordan). Diaconess Hospital, Utrecht (Director: Dr. M.A. v. Melle). Pathological Institute, University of Utrecht (Head: Prof. Dr. A. de Minjer)

Article

Publisher ID: 179619 Other ID: Nephron 1968;5:81–89

DOI: 10.1159/000179619

PubMed ID: 5655615

SO-VID: cbc1e096-d19d-4a59-885b-8c542d981640

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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Page count

Pages: 9

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Self URI (application/pdf): https://www.karger.com/Article/Pdf/179619

Self URI (text/html): https://www.karger.com/Article/FullText/179619

Self URI (journal page): https://www.karger.com/SubjectArea/Nephrology

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