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      Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States.

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          Abstract

          Idiosyncratic drug-induced liver injury (DILI) is among the most common causes of acute liver failure in the United States, accounting for approximately 13% of cases. A prospective study was begun in 2003 to recruit patients with suspected DILI and create a repository of biological samples for analysis. This report summarizes the causes, clinical features, and outcomes from the first 300 patients enrolled.

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          Author and article information

          Journal
          Gastroenterology
          Gastroenterology
          Elsevier BV
          1528-0012
          0016-5085
          Dec 2008
          : 135
          : 6
          Affiliations
          [1 ] Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA. nchalasa@iupui.edu
          Article
          S0016-5085(08)01674-0 NIHMS444171
          10.1053/j.gastro.2008.09.011
          3654244
          18955056
          cc0c8e51-234a-4a76-ace5-eda20d3648e9
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