- Record: found
- Abstract: not found
- Article: not found
Evaluating the landscape of gene cooperativity with receptor tyrosine kinases in liver tumorigenesis using transposon-mediated mutagenesis
Yannan Fan , Sehrish K. Bazai , Fabrice Daian , Maria Arechederra , Sylvie Richelme , Nuri A. Temiz , Annie Yim , Bianca H. Habermann , Rosanna Dono , David A. Largaespada , Flavio Maina
December 2018
December 2018
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
The variety of alterations found in hepatocellular carcinoma (HCC) makes the identification
of functionally relevant genes and their combinatorial actions in tumorigenesis challenging.
Deregulation of receptor tyrosine kinases (RTKs) is frequent in HCC, yet little is
known about the molecular events that cooperate with RTKs and whether these cooperative
events play an active role at the root of liver tumorigenesis.
Related collections
Author and article information
Journal
Journal of Hepatology
Journal of Hepatology
Elsevier BV
01688278
December
2018
December
2018
Article
10.1016/j.jhep.2018.11.027
30529386
©
2018
Product
Self URI (article page):
https://linkinghub.elsevier.com/retrieve/pii/S0168827818325789