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Plethysmography and impulse oscillometry assessment of tiotropium and ipratropium bromide; a randomized, double-blind, placebo-controlled, cross-over study in healthy subjects.
D Singh
1 ,
R Tal-Singer ,
I Faiferman ,
S Lasenby ,
A Henderson ,
D Wessels ,
A Goosen ,
N Dallow ,
R Vessey ,
M Goldman
Apr 2006
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Abstract
Spirometry, plethysmography and impulse oscillometry (IOS) measure different aspects of lung function. These methods have not been compared for their ability to assess long- and short-acting anticholinergic agents. We therefore performed a double-blind, placebo-controlled, four-way cross-over study in 30 healthy subjects.