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      Improved accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia.

      1 ,

      Anesthesia and analgesia

      Ovid Technologies (Wolters Kluwer Health)

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          Abstract

          Methemoglobin in the blood cannot be detected by conventional pulse oximetry and may bias the oximeter's estimate (Spo(2)) of the true arterial functional oxygen saturation (Sao(2)). A recently introduced "pulse CO-oximeter" (Masimo Rainbow SET® Radical-7) that measures SpMet, a noninvasive measurement of the percentage of methemoglobin in arterial blood (%MetHb), was shown to read spuriously high values during hypoxia. In this study we sought to determine whether the manufacturer's modifications have improved the device's ability to detect and accurately measure methemoglobin and deoxyhemoglobin simultaneously.

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          Author and article information

          Journal
          Anesth. Analg.
          Anesthesia and analgesia
          Ovid Technologies (Wolters Kluwer Health)
          1526-7598
          0003-2999
          Nov 2010
          : 111
          : 5
          Affiliations
          [1 ] Department of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, CA 94143-0648, USA. feinerj@anesthesia.ucsf.edu
          Article
          ANE.0b013e3181f46da8
          10.1213/ANE.0b013e3181f46da8
          20841412

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