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      Review of the discard and/or refusal rate of offered donor hearts to pediatric waitlisted candidates.

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          Abstract

          We aimed to review current literature on the discard rate of donor hearts offered to pediatric recipients and assess geographical differences. Consequences and ways to reduce the discard rate are discussed. A systemic review on published literature on pediatric transplantation published in English since 2010 was undertaken. Additionally, a survey was sent to international OPOs with the goal of incorporating responses from around the world providing a more global picture. Based on the literature review and survey, there is a remarkably wide range of discard and/or refusal for pediatric hearts offered for transplant, ranging between 18% and 57% with great geographic variation. The data suggest that that the overall refusal rate may have decreased over the last decade. Reasons for organ discard were difficult to identify from the available data. Although the refusal rate of pediatric donor hearts seems to be lower compared to that reported in adults, it is still as high as 57% with geographic variation.

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          Author and article information

          Journal
          Pediatr Transplant
          Pediatric transplantation
          Wiley
          1399-3046
          1397-3142
          May 2020
          : 24
          : 3
          Affiliations
          [1 ] Division of Cardiac Surgery, Pediatric Heart Center, University Children's Hospital Zurich, Zurich, Switzerland.
          [2 ] Children's Hospital Colorado, Denver, CO, USA.
          [3 ] Stanford University, Palo Alto, CA, USA.
          [4 ] Nationwide Children's Hospital, Columbus, OH, USA.
          [5 ] Fundacion Cardiovascular de Colombia, Bucaramanga City, Colombia.
          [6 ] Congenital Heart Center, University of Florida, Gainesville, FL, USA.
          [7 ] Washington University School of Medicine, St Louis, MO, USA.
          [8 ] University of Utah, Salt Lake City, UT, USA.
          [9 ] Pediatric Cardiac Center, Hungarian Institute of Cardiology, Budapest, Hungary.
          [10 ] Division of Pediatric Cardiology, University of Texas Southwestern Medical Center, Children's Medical Center, Dallas, TX, USA.
          [11 ] Department of Congenital Heart Disease/Pediatric Cardiology, Deutsches Herzzentrum, Berlin, Germany.
          [12 ] Department of Cardiovascular and Thoracic Surgery, Children's Medical Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.
          [13 ] Labatt Family Heart Centre, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
          Article
          10.1111/petr.13674
          32198804
          cdb0f5ac-3010-4a49-aaee-ea18c38dc8c1
          History

          pediatric heart transplantation,discrad rate,heart donor,refusal rate

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