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      Replacement Therapy in Hypothalamo-Pituitary Insufficiency after Childhood: Management in the Adult

      Hormone Research in Paediatrics

      S. Karger AG

      Adult, GH, Hypopituitarism, Therapy

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          Abstract

          Replacement therapy in cases of hypopituitarism in the adult has improved dramatically in the last decade. After initial detailed investigation of the extent of the hormone deficiency, the replacement therapy is tailored to the particular needs of the individual. Over-replacement with glucocorticoids must be avoided. Replacement of gonadal steroids is simpler than the induction of fertility. Gonadotrophin-releasing hormone has simplified fertility induction in cases of hypothalamic origin of the disease. Altered body composition and poor quality of life reversible with GH therapy have emphasised the importance of GH in the adult.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          978-3-8055-5290-5
          978-3-318-01979-7
          1663-2818
          1663-2826
          1990
          1990
          02 December 2008
          : 33
          : Suppl 4
          : 45-51
          Affiliations
          United Medical and Dental School of Guy’s and St. Thomas’ Hospitals, St. Thomas Hospital, London, UK
          Article
          181583 Horm Res 1990;33:45–51
          10.1159/000181583
          2174019
          © 1990 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 7
          Categories
          The Seville hGH Symposium

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