An intriguing electrochemical impedance aptasensor based on a porous organic framework supported silver nanoparticles for ultrasensitively detecting theophylline

Organic conjugated polymers (conducting polymers) have emerged as potential candidates for electrochemical sensors. Due to their straightforward preparation methods, unique properties, and stability in air, conducting polymers have been applied to energy storage, electrochemical devices, memory devices, chemical sensors, and electrocatalysts. Conducting polymers are also known to be compatible with biological molecules in a neutral aqueous solution. Thus, these are extensively used in the fabrication of accurate, fast, and inexpensive devices, such as biosensors and chemical sensors in the medical diagnostic laboratories. Conducting polymer-based electrochemical sensors and biosensors play an important role in the improvement of public health and environment because rapid detection, high sensitivity, small size, and specificity are achievable for environmental monitoring and clinical diagnostics. In this review, we summarized the recent advances in conducting polymer-based electrochemical sensors, which covers chemical sensors (potentiometric, voltammetric, amperometric) and biosensors (enzyme based biosensors, immunosensors, DNA sensors).