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Predictors of fatigue following the onset of infectious mononucleosis.
B Candy
1 ,
T Chalder ,
A J Cleare ,
A Peakman ,
A Skowera ,
S Wessely ,
J Weinman ,
M Zuckerman ,
M Hotopf
Jul 2003
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Abstract
Infectious mononucleosis (IM) is a risk factor for chronic fatigue. Reduced activity is the most consistent factor found to be associated with poor outcome following the onset of infectious mononucleosis. However, little is known about the biological mechanisms involved in the pathogenesis of chronic fatigue following IM and no study, so far, has examined the relation between certain illness beliefs and poor outcome. This study explored immunological, endocrine, behavioural and cognitive responses to the acute illness and assessed which components of these groups of risk factors predicted a chronic course.