Blog
About

  • Record: found
  • Abstract: found
  • Article: not found

Acid adaptation in Streptococcus mutans UA159 alleviates sensitization to environmental stress due to RecA deficiency.

1 , , ,

FEMS microbiology letters

Read this article at

ScienceOpenPubMed
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Abstract

      A RecA-deficient stain of Streptococcus mutans, isolated previously, was found to be more susceptible than the prototroph organism to acid killing and also showed reduced colony-forming ability on sucrose-containing medium. The deficient strain was able to grow in chemostat culture at a low pH value of 5 and did not show reduced capacity to produce acid in standard pH-drop experiments with excess glucose. Moreover, it was able to undergo an adaptive response when grown at a low pH to become more resistant to acid killing and also to killing by ultraviolet radiation or hydrogen peroxide. In fact, after adaptation, it was nearly as resistant as the prototroph strain. These findings were interpreted, in part, in terms of an acid-inducible DNA repair system which functions independently of RecA.

      Related collections

      Author and article information

      Affiliations
      [1 ] Department of Dental Research, University of Rochester, School of Medicine and Dentistry, New York 14642.
      Journal
      FEMS Microbiol. Lett.
      FEMS microbiology letters
      0378-1097
      0378-1097
      Mar 01 1995
      : 126
      : 3
      7729669
      0378109795000192

      Comments

      Comment on this article