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      Stimuli-responsive bio-based polymeric systems and their applications

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          Abstract

          This article highlights the properties of stimuli-responsive bio-based polymeric systems and their main intelligent applications.

          Abstract

          Stimuli-responsive bio-based polymeric systems are gaining considerable attention as intelligent versatile tools that show great potential in various fields. In this review, an overview is given of recent developments of stimuli-responsive bio-based polymeric systems. The characteristics of bio-based polymers in different applications are discussed and the superiority of these advanced stimuli-responsive bio-based polymeric systems is highlighted. Furthermore, several emerging applications of these systems including intelligent drug delivery, responsive food packaging and smart water treatment are discussed and the section of intelligent drug delivery is emphasized in detail. Finally, the respective prospects and limitations inherent to these systems are addressed.

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          Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors

          Graphical abstract Nanotechnology may revolutionize the food industry by providing stronger, high-barrier packaging materials, more potent antimicrobial agents, and a host of sensors which can detect trace contaminants, gasses or microbes in packaged foods. Highlights ► Focuses on the use of nanomaterials in food packaging and sensing applications. ► Polymer nanocomposites offer high gas barriers, strength, and flame retardancy. ► Silver and metal oxide nanoparticles are potent biocides. ► Nanosensors and assays detect gasses, small molecules and microorganisms. ► Economic outlook and health and safety implications are also briefly reviewed.
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            Polysaccharides-based nanoparticles as drug delivery systems.

            Natural polysaccharides, due to their outstanding merits, have received more and more attention in the field of drug delivery systems. In particular, polysaccharides seem to be the most promising materials in the preparation of nanometeric carriers. This review relates to the newest developments in the preparation of polysaccharides-based nanoparticles. In this review, four mechanisms are introduced to prepare polysaccharides-based nanoparticles, that is, covalent crosslinking, ionic crosslinking, polyelectrolyte complex, and the self-assembly of hydrophobically modified polysaccharides.
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              On the importance and mechanisms of burst release in matrix-controlled drug delivery systems.

              Although the significance of burst release in controlled delivery systems has not been entirely ignored, no successful theories have been put forth to fully describe the phenomenon. Despite the fact that the fast release of drug in a burst stage is utilized in certain drug administration strategies, the negative effects brought about by burst can be pharmacologically dangerous and economically inefficient. Therefore a thorough understanding of the burst effect in controlled release systems is undoubtedly necessary. In this article, we review experimental observations of burst release in monolithic polymer controlled drug delivery systems, theories of the physical mechanisms causing burst, some of the unique ideas used to prevent burst, and the treatment of burst release in controlled release models.
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                Author and article information

                Journal
                JMCBDV
                Journal of Materials Chemistry B
                J. Mater. Chem. B
                Royal Society of Chemistry (RSC)
                2050-750X
                2050-7518
                January 30 2019
                2019
                : 7
                : 5
                : 709-729
                Affiliations
                [1 ]College of Chemical Engineering, Jiangsu Provincial Key Lab for the Chemistry and Utilization of Agro-forest Biomass, Jiangsu Key Lab of Biomass-based Green Fuels and Chemicals, Nanjing Forestry University (NFU)
                [2 ]Nanjing 210037
                [3 ]P. R. China
                [4 ]Lab General Biochemistry & Physical Pharmacy, Department of Pharmaceutics, Ghent University
                [5 ]Belgium
                [6 ]College of Materials Science and Engineering, Nanjing Forestry University (NFU)
                [7 ]School of Material Science and Engineering, Xi’an Jiaotong University
                [8 ]Xi’an 710049
                [9 ]Laboratory of Biopolymer based Functional Materials, Nanjing Forestry University
                [10 ]Nanjing
                Article
                10.1039/C8TB02491J
                32254845
                cee08f01-88f7-4be5-91e2-e88fecc28e0a
                © 2019

                http://rsc.li/journals-terms-of-use

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