Identification of drug-target interaction from interactome network with 'guilt-by-association' principle and topology features.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Identifying drug-target protein interaction is a crucial step in the process of drug research and development. Wet-lab experiment are laborious, time-consuming and expensive. Hence, there is a strong demand for the development of a novel theoretical method to identify potential interaction between drug and target protein.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Bioinformatics

Title: Bioinformatics (Oxford, England)

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1367-4811

ISSN (Print): 1367-4803

Publication date (Electronic): Apr 01 2016

Volume: 32

Issue: 7

Affiliations

[1 ] School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Guangzhou 510006, People's Republic of China.

[2 ] School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China.

[3 ] SYSU-CMU Shunde International Joint Research Institute, Shunde 528300, People's Republic of China and School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China.

Article

Publisher Item ID: btv695

DOI: 10.1093/bioinformatics/btv695

PubMed ID: 26614126

SO-VID: cf2dcdb6-23ee-4985-91f4-49db4280164d

History

Data availability:

Comments

Comment on this article

scite_

Cited by 23

See all cited by