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      Adverse childhood experience patterns, major depressive disorder, and substance use disorder in older adults

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          Abstract

          <p class="first" id="d19109579e83">This article investigates distinct patterns of adverse childhood experiences (ACEs) in a representative sample of US older adults, and how the ACEs patterns relate to major depression and substance use disorder (SUD). </p>

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          In utero programming of chronic disease.

          1. Many human fetuses have to adapt to a limited supply of nutrients. In doing so they permanently change their structure and metabolism. 2. These 'programmed' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related disorders stroke, diabetes and hypertension. 3. This review examines the evidence linking these diseases to fetal undernutrition and provides an overview of previous studies in this area.
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            Author and article information

            Journal
            Aging & Mental Health
            Aging & Mental Health
            Informa UK Limited
            1360-7863
            1364-6915
            March 04 2021
            November 26 2019
            March 04 2021
            : 25
            : 3
            : 484-491
            Affiliations
            [1 ]Virginia Commonwealth University School of Social Work, Richmond, VA, USA
            Article
            10.1080/13607863.2019.1693974
            31769297
            cf5231df-5c45-4a41-aee5-2f858f843359
            © 2021
            History

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