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      Case-control and two-gate designs in diagnostic accuracy studies.

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          Abstract

          In some diagnostic accuracy studies, the test results of a series of patients with an established diagnosis are compared with those of a control group. Such case-control designs are intuitively appealing, but they have also been criticized for leading to inflated estimates of accuracy.

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          Author and article information

          Journal
          Clin Chem
          Clinical chemistry
          American Association for Clinical Chemistry (AACC)
          0009-9147
          0009-9147
          Aug 2005
          : 51
          : 8
          Affiliations
          [1 ] Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. a.rutjes@amc.uva.nl
          Article
          clinchem.2005.048595
          10.1373/clinchem.2005.048595
          15961549
          cf6f6e1f-3aa2-46fb-911b-acb2203f6014
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