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      Pamidronate-induced remission of pain associated with hypertrophic pulmonary osteoarthropathy in chemoendocrine therapy-refractory inoperable metastatic breast carcinoma.

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          Abstract

          We describe an extremely rare case of a woman with pulmonary metastatic disease from breast cancer, who presented with features of hypertrophic pulmonary osteoarthropathy (HPOA). Pain associated with HPOA may be extremely disabling and resistant to treatment. Treatment with pamidronate, an inhibitor of osteoclastic bone resorption, given every 2 weeks by i.v. drip infusion, led to rapid disappearance of uncontrolled pain caused by HPOA.

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          Author and article information

          Journal
          Anticancer Drugs
          Anti-cancer drugs
          0959-4973
          0959-4973
          Oct 2001
          : 12
          : 9
          Affiliations
          [1 ] Department of Surgery, Affiliated Kihoku Hospital, Wakayama Medical University, 219 Myouji, Katsuragicho, Itogun, Wakayama 649-7113, Japan. suzuma@mail.wakayama-med.ac.jp
          Article
          11593054

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