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Endoscopic and Molecular Characterization of Colorectal Sessile Serrated Adenoma/polyps with Cytological Dysplasia.
Yoshihito Tanaka
1 ,
Hiro-O Yamano
2 ,
Eiichiro Yamamoto
3 ,
Hiro-O Matushita
1 ,
Hironori Aoki
4 ,
Kenjiro Yoshikawa
1 ,
Ryo Takagi
1 ,
Eiji Harada
1 ,
Michiko Nakaoka
1 ,
Yuko Yoshida
1 ,
Makoto Eizuka
5 ,
Tamotsu Sugai
5 ,
Hiromu Suzuki
6 ,
Hiroshi Nakase
2
May 10 2017
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Abstract
Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with BRAF mutation and the CpG island methylator phenotype (CIMP), develop cytological dysplasia (CD) during the progression of colorectal tumorigenesis. In the present study, we aimed to clarify the endoscopic and molecular signatures of SSA/Ps, with and without CD.