Time Course and Diagnostic Accuracy of Glial and Neuronal Blood Biomarkers GFAP and UCH-L1 in a Large Cohort of Trauma Patients With and Without Mild Traumatic Brain Injury

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Abstract

Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1) have been widely studied and show promise for clinical usefulness in suspected traumatic brain injury (TBI) and concussion. Understanding their diagnostic accuracy over time will help translate them into clinical practice.

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Journal

Title: JAMA Neurology

Abbreviated Title: JAMA Neurol

Publisher: American Medical Association (AMA)

ISSN (Print): 2168-6149

Publication date Created: May 01 2016

Publication date (Print): May 01 2016

Volume: 73

Issue: 5

Page: 551

Affiliations

[1 ]Department of Emergency Medicine, Orlando Regional Medical Center, Orlando, Florida

[2 ]Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Richmond3Department of Neurosurgery, Virginia Commonwealth University, Richmond

[3 ]Division of Emergency Medicine, Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan

[4 ]Division of Emergency Medicine, Washington University School of Medicine in St Louis, Missouri

[5 ]US Department of Defense, Silver Springs, Maryland

[6 ]Brain Health, Harpers Ferry, West Virginia

Article

DOI: 10.1001/jamaneurol.2016.0039

PubMed ID: 27018834

SO-VID: cfecb0fa-8afa-458b-9ca2-1215ec5dfae8

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