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      Shift work and the risk of cardiovascular disease among workers in cocoa processing company, Tema

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          Abstract

          Objective

          Shift work has been implicated in cardiovascular disease (CVD), a major cause of death globally. The aim of this study was to evaluate the risk of developing CVD in shift work.

          Design

          A cross-sectional study involving secondary analysis of shift and non-shift work from an industry in Ghana.

          Participants

          Two hundred (113 shift and 87 non-shift) consecutive workers who consented were recruited into the study. A structured questionnaire was administered to deduce information on participant’s age, alcohol consumption pattern, smoking habits, history of diabetes, stroke and hypertension.

          Results

          Shift workers were found to be associated with higher body mass index (26.9 ± 4.6 vs 25.2 ± 3.3, p = 0.013); fasting blood glucose (5.9 ± 1.8 vs 5.3 ± 0.8, p ≤ 0.0001); glycated haemoglobin (4.9 ± 0.9 vs 4.2 ± 0.8, p ≤ 0.0001); high sensitivity C-reactive protein (2.5 ± 1.1 vs 1.8 ± 1.1, p < 0.0001); total cholesterol (5.9 ± 1.3 vs 5.2 ± 1.7, p = 0.002); triglycerides (1.3 ± 0.8 vs 1.1 ± 0.6, p = 0.015) and LDL cholesterol (3.6 ± 0.9 vs 3.2 ± 1.3, p = 0.04) than controls. Shift work however, had no associations with HDL-cholesterol.

          Conclusion

          It can be concluded that shift work is associated with risk factors of CVD.

          Electronic supplementary material

          The online version of this article (doi:10.1186/s13104-015-1750-3) contains supplementary material, which is available to authorized users.

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          Most cited references25

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          Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27,485 people.

          To explore how metabolic risk factors for cardiovascular disease (CVD) differ between shift workers and day workers in a defined population. Shift work has been associated with an increased risk of CVD. Risk factors and causal pathways for this association are only partly known. A working population of 27,485 people from the Västerbotten intervention program (VIP) has been analysed. Cross sectional data, including blood sampling and questionnaires were collected in a health survey. Obesity was more prevalent among shift workers in all age strata of women, but only in two out of four age groups in men. Increased triglycerides (>1.7 mmol/l) were more common among two age groups of shift working women but not among men. Low concentrations of high density lipoprotein (HDL) cholesterol (men<0.9 and women<1.0 mmol/l) were present in the youngest age group of shift workers in both men and women. Impaired glucose tolerance was more often found among 60 year old women shift workers. Obesity and high triglycerides persisted as risk factors in shift working men and women after adjusting for age and socioeconomic factors, with an OR of 1.4 for obesity and 1.1 for high triglyceride concentrations. The relative risks for women working shifts versus days with one, two, and three metabolic variables were 1.06, 1.20, and 1.71, respectively. The corresponding relative risks for men were 0.99, 1.30, and 1.63, respectively. In this study, obesity, high triglycerides, and low concentrations of HDL cholesterol seem to cluster together more often in shift workers than in day workers, which might indicate an association between shift work and the metabolic syndrome.
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            Health effects of shift work and extended hours of work

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              Rotating shift work and the metabolic syndrome: a prospective study.

              Several studies have documented on the elevated cardiovascular risk among shift workers. In order to further explore this relation, we aimed at assessing the association between rotating shift work and the incidence of the metabolic syndrome (MetS). In this population-based prospective study, 1529 employees from several large Belgian companies were followed for a median observation period of 6.6 years with respect to the onset of the MetS and its separate components. At baseline, 309 men (20.2%) were rotating shift workers. The MetS incidence rate in these shift workers (60.6 per 1000 person-years) was increased in comparison with day workers (37.2 per 1000 person-years) with an odds ratio (95% CI) of 1.77 (1.34-2.32). Multivariate adjustment for potential lifestyle and work-related confounders did only marginally affect the strength of the association. The risk for the development of MetS gradually increased independently with accumulated years of shift work. Rotating shift work not only had an impact on MetS as a cluster of conditions but on each of its individual components as well. Hence, prospective evidence was found that rotating shift work increases the risk for developing the MetS over a period of 6 years.
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                Author and article information

                Contributors
                henryasare-anane.gh@hotmail.com
                alacaps123@yahoo.co.uk
                +233 (0) 244267217 , Emmanuel.ofori@unil.ch
                presmubarak@gmail.com
                Amanquahseth@gmail.com
                Journal
                BMC Res Notes
                BMC Res Notes
                BMC Research Notes
                BioMed Central (London )
                1756-0500
                18 December 2015
                18 December 2015
                2015
                : 8
                : 798
                Affiliations
                [ ]Department of Chemical Pathology, School of Biomedical and Allied Health Sciences (S.B.A.H.S), University of Ghana, P. O. Box 4236, Korle-Bu, Accra, Ghana
                [ ]K.B.T.H, Korle-Bu, Accra, Ghana
                [ ]Department of Immunology, School of Biomedical and Allied Health Sciences (S.B.A.H.S), Korle-Bu, Accra, Ghana
                Article
                1750
                10.1186/s13104-015-1750-3
                4683766
                26682743
                d0ab2f08-0799-4052-9cc3-853b655eeaae
                © Asare-Anane et al. 2015

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 13 February 2015
                : 25 November 2015
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2015

                Medicine
                cardiovascular disease,shift work,body mass index,dyslipidemia,hypertension
                Medicine
                cardiovascular disease, shift work, body mass index, dyslipidemia, hypertension

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