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      Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes.

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      Publication date:
      Journal: Circulation Research
      Publisher: Ovid Technologies (Wolters Kluwer Health)

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          Abstract

          autophagy, a bulk degradation process of cytosolic proteins and organelles, is protective during nutrient starvation in cardiomyocytes (CMs). However, the underlying signaling mechanism mediating autophagy is not well understood.

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          PubMed ID:: 20947830
          PMC ID:: 3011986
          DOI:: 10.1161/CIRCRESAHA.110.227371

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