Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial.

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Abstract

Regular paracetamol is the recommended first-line analgesic for acute low-back pain; however, no high-quality evidence supports this recommendation. We aimed to assess the efficacy of paracetamol taken regularly or as-needed to improve time to recovery from pain, compared with placebo, in patients with low-back pain.

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Journal

Journal ID (iso-abbrev): Lancet

Title: Lancet (London, England)

ISSN (Electronic): 1474-547X

ISSN (Print): 0140-6736

Publication date (Electronic): Nov 1 2014

Volume: 384

Issue: 9954

Affiliations

[1 ] The George Institute for Global Health, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia; Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia. Electronic address: cwilliams@georgeinstitute.org.au.

[2 ] The George Institute for Global Health, Sydney Medical School, University of Sydney, Camperdown, NSW, Australia.

[3 ] Faculty of Pharmacy and Centre for Education and Research in Ageing, University of Sydney, Sydney, NSW, Australia.

[4 ] Faculty of Human Sciences, Macquarie University, Sydney, NSW, Australia.

[5 ] Clinical Pharmacology, University of New South Wales and St Vincent's Hospital, Darlinghurst, NSW, Australia.

Article

Publisher Item ID: S0140-6736(14)60805-9

DOI: 10.1016/S0140-6736(14)60805-9

PubMed ID: 25064594

SO-VID: d12ed419-7063-4ee3-a7c8-fd7ef35c9f85

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