6
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Disfunción ventricular izquierda subclínica en diabéticos tipo I con 10 o más años de evolución de la diabetes Translated title: Disfunción ventricular izquierda subclínica en diabéticos tipo I con 10 o más años de evolución de la diabetes Subclinical left ventricular dysfunction in type 1 diabetics with 10 or more years of diabetes progression

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Se realizó un estudio transversal en 32 diabéticos tipo 1 con 10 o más años de evolución, con edades entre 17 y 40 años, para conocer la frecuencia de disfunción ventricular izquierda (DVI) subclínica y sus factores asociados. Se excluyeron los pacientes que presentaban valvulopatía, cardiopatía isquémica, hipertensión arterial y otras enfermedades que provocan miocardiopatía. A todos se les realizó una historia clínica completa y se les indicó: glucemia en ayunas, hemoglobina glucosilada (HbA1), colesterol total, triglicéridos totales, lipoproteína de alta densidad (HDL-colesterol), excreción urinaria de albúmina (EUA), velocidad de conducción nerviosa motora y sensitiva en los miembros inferiores, electrocardiograma y ecocardiograma a modo M, bidimensional y con Doppler pulsado. Para el diagnóstico ecocardiográfico de DVI se adoptaron los criterios propuestos por la Sociedad Americana de Ecocardiografía. Se comprobó DVI en el 34,3 %. Se observaron alteraciones estructurales cardíacas en el 18,75 %. Se presentó neuropatía periférica en 8/11 pacientes con DVI (72,7 %). Los niveles de EUA fueron significativamente mayores en los afectados de DVI (233,4 ± 176 mg/L). El engrosamiento de septum interventricular y de la pared posterior fue significativamente mayor en pacientes con DVI. Se concluyó que la DVI es una complicación frecuente en el diabético tipo 1, lo que obliga a su búsqueda sistemática en este grupo de pacientes

          Translated abstract

          A cross-sectional study of 32 type 1 diabetics aged 17-40 years, with 10 or more years of diabetes profession was conducted to find out the frequency of subclinical left ventricular dysfunction (LVD) and its associated factors. Those patients presenting with valvulopathy, ischemic heart disease, blood hypertension and other diseases leading to myocardiopathy, were excluded. Their complete medical histories were made and they were indicated the following: glycemia in fasting conditions, glycosylated hemoglobin, total cholesterol, total triglycerides, high density lipoprotein, urine excretion of albumin, speed of motor and sensitive nerve conduction in lower limbs, electrocardiogram and pulsed Doppler bidimensional M mode echocardiography. For the echocardiographic diagnosis of left ventricular dysfunction, the criteria submitted by the American Society of Echocardiography were adopted. LVD was confirmed in 34.3 % of patients. Structural cardiac abnormalities were observed in 18.75% of cases; peripheral neuropathy was found in 8 of 11 patients with LVD (72.7%); the levels of urine excretion of albumin were significantly higher in those affected by LVD(233.4±176 mg/L).The thickening of the interventricular septum and the posterior wall was markedly greater in patients with LVD. It was concluded that LVD is a frequent complication in type 1 diabetics, which makes it necessary to systematically look for this disorder in this group of patients

          Related collections

          Most cited references55

          • Record: found
          • Abstract: not found
          • Article: not found

          The electrocardiogram in population studies. A classification system.

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Meta-analysis of effects of intensive blood-glucose control on late complications of type I diabetes.

            Tight blood glucose control has been speculated to reduce late complications in insulin-dependent diabetics but results from individual studies have been inconsistent. We have done a meta-analysis of sixteen randomised trials of intensive therapy to estimate its impact on the progression of diabetic retinopathy and nephropathy and the risks of severe side-effects. In the intensive therapy group, the risk of retinopathy progression was insignificantly higher after 6-12 months of intensive control (odds ratio [OR] 2.11). After more than two years of intensive therapy the risk of retinopathy progression was lower (OR 0.49 [95% confidence interval 0.28-0.85], p = 0.011). The risk of nephropathy progression was also decreased significantly (OR 0.34 [0.20-0.58], p < 0.001). The incidence of severe hypoglycaemia increased by 9.1 episodes per 100 person-years (95% Cl -1.4 to +19.6) in the intensively treated patients. The incidence of diabetic ketoacidosis increased by 12.6 episodes per 100 person-years (95% Cl, 8.7-16.5) in the patients on continuous subcutaneous insulin infusion. Long-term intensive blood glucose control significantly reduces the risk of diabetic retinopathy and nephropathy progression but long-term continuous subcutaneous insulin infusion was associated with an increased incidence of diabetic ketoacidosis, and intensive therapy may cause more severe hypoglycaemic reactions.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Capillary microaneurysms in the human diabetic heart.

                Bookmark

                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                end
                Revista Cubana de Endocrinología
                Rev Cubana Endocrinol
                Editorial Ciencias Médicas (Ciudad de la Habana )
                1561-2953
                August 2001
                : 12
                : 2
                : 0
                Affiliations
                [1 ] Hospital Clinicoquirúrgico Comandante Manuel Fajardo Cuba
                [2 ] Instituto Nacional de Endocrinología Cuba
                [3 ] Instituto Superior de Medicina Militar Dr. Luis Díaz Soto Cuba
                Article
                S1561-29532001000200006
                d19c5334-7242-4fdf-b05a-f128955c44c3

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Cuba

                Self URI (journal page): http://scielo.sld.cu/scielo.php?script=sci_serial&pid=1561-2953&lng=en
                Categories
                ENDOCRINOLOGY & METABOLISM

                Endocrinology & Diabetes
                DIABETES MELLITUS, INSULIN-DEPENDENT,HEART DISEASES,ECHOCARDIOGRAPHY,VENTRICULAR DYSFUNCTION, LEFT,RISK FACTORS,DIABETES MELLITUS INSULINO-DEPENDIENTE,CARDIOPATIAS,ECOCARDIOGRAFIA,DISFUNCION VENTRICULAR IZQUIERDA,FACTORES DE RIESGO

                Comments

                Comment on this article