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      Changes of Maternal and Fetal Pituitary-Adrenocortical Functions during Human Labour

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          The results of maternal 11-hydroxycorticoid (11-OHCS) determination on blood obtained from four stages of 44 spontaneous labour cases showed a strong and time-related maternal adrenocortical activation during vaginal delivery. The high 11-OHCS level in the cord blood and the increase of the 11-OHCS concentration in the amniotic fluid suggested the same response of the fetal adrenal. However, in 14 cases of elective caesarean sections the 11-OHCS levels in the cord blood and the amniotic fluid did not rise in spite of the elevated maternal plasma 11-OHCS content.

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          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          25 November 2008
          : 11
          : 5
          : 213-217
          Department of Pathophysiology, University Medical School, Department of Obstetrics and Gynecology, City Hospital, and Department of Obstetrics and Gynecology, University Medical School, Szeged
          179057 Horm Res 1979;11:213–217
          © 1979 S. Karger AG, Basel

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