Changing practice: red blood cell typing by molecular methods for patients with sickle cell disease.

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Abstract

Extended red blood cell (RBC) antigen matching is recommended to limit alloimmunization in patients with sickle cell disease (SCD). DNA-based testing to predict blood group phenotypes has enhanced availability of antigen-negative donor units and improved typing of transfused patients, but replacement of routine serologic typing for non-ABO antigens with molecular typing for patients has not been reported.

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Journal

Journal ID (iso-abbrev): Transfusion

Title: Transfusion

Publisher: Wiley-Blackwell

ISSN (Electronic): 1537-2995

ISSN (Print): 0041-1132

Publication date (Electronic): Jun 2015

Volume: 55

Issue: 6 Pt 2

Affiliations

[1 ] Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

[2 ] Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

[3 ] Immunohematology and Genomics Laboratory, New York Blood Center, New York City, New York.

Article

DOI: 10.1111/trf.12987

PubMed ID: 25573464

SO-VID: d1cf3acc-c1a2-4c33-9881-0f3f79173ed3

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