+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found

      Serum and Urinary Estrone Sulfate during the Menstrual Cycle, Measured by a Direct Radioimmunoassay, and Fate of Exogenously Injected Estrone Sulfate

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          Serum and early-morning urinary levels of estrone sulfate during the menstrual cycle were measured by a direct radioimmunoassay without hydrolysis. These levels were high and showed prominent peaks [serum, 2.67 ± 0.37 ng/ml (mean ± SE); urine, 5.82 ± 2.3 µg/l] around the day of the preovulatory estradiol-17β peak, and increased again during the luteal phase. Following intravenous injection of estrone sulfate, serum estrone sulfate, estrone and estradiol-17β were measured. The conversion of estrone sulfate to estrone and/or estradiol-17β was very small during their transit in the general circulation.

          Related collections

          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          28 November 2008
          : 27
          : 2
          : 61-68
          aDepartment of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine, Kyoto; bPharmaceutical Institute, Tohoku University, Sendai, Japan
          180788 Horm Res 1987;27:61–68
          © 1987 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 8
          Original Paper


          Comment on this article