The digital multimedia technology has transformed the tertiary education environment, changing lecturers’ role who are required to develop multimedia teaching aids to sustain effective teaching and learning engagement. As interface designers, it is vital to produce good design, which effectively communicates the teaching and learning content. This paper provides an empirical evaluation on what are the interface design principles characteristics contributing to multimedia teaching aid design appearance, outlined from analysis towards interface design principles applied in Malaysian tertiary institutions’ multimedia teaching aids. Although the sample of this study is locally based, the outcomes of this paper could extensively be a guideline for other countries.