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      Ocular Penetration and Pharmacokinetics of Ripasudil Following Topical Administration to Rabbits.

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          Abstract

          We evaluated the ocular pharmacokinetics of ripasudil (K-115), a selective Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, following topical administration to rabbits.

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          Author and article information

          Journal
          J Ocul Pharmacol Ther
          Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
          Mary Ann Liebert Inc
          1557-7732
          1080-7683
          September 2016
          : 32
          : 7
          Affiliations
          [1 ] 1 Tokyo New Drug Research Laboratories, Kowa Co., Ltd. , Tokyo, Japan .
          [2 ] 2 Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama , Toyama, Japan .
          Article
          10.1089/jop.2016.0028
          27463221
          d2636772-ea04-49e6-9e40-c549ea0de1b3
          History

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