Influence of CRP, IL6, and TNFA gene polymorphisms on circulating levels of C-reactive protein in Mexican adolescents.

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Abstract

Obesity correlates with a chronic and low-grade inflammation status. C-reactive protein (CRP) measurement has been used as an independent risk marker for future cardiovascular events. CRP level shows interindividual variability due to environmental and genetic factors. The aim of this study was to assess the association of functional polymorphisms on CRP, IL6, and TNFA genes with serum CRP levels in Mexican mestizo adolescents.

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Journal

Journal ID (iso-abbrev): Arch. Med. Res.

Title: Archives of medical research

ISSN (Electronic): 1873-5487

ISSN (Print): 0188-4409

Publication date (Electronic): Aug 2010

Volume: 41

Issue: 6

Affiliations

[1 ] Molecular Medicine Division, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México. francisco.mendozac@imss.gob.mx

Article

Publisher Item ID: S0188-4409(10)00263-8

DOI: 10.1016/j.arcmed.2010.08.015

PubMed ID: 21044752

SO-VID: d2e935bf-55ae-4816-9311-c6262bf43f54

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