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Influence of CRP, IL6, and TNFA gene polymorphisms on circulating levels of C-reactive protein in Mexican adolescents.

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      Abstract

      Obesity correlates with a chronic and low-grade inflammation status. C-reactive protein (CRP) measurement has been used as an independent risk marker for future cardiovascular events. CRP level shows interindividual variability due to environmental and genetic factors. The aim of this study was to assess the association of functional polymorphisms on CRP, IL6, and TNFA genes with serum CRP levels in Mexican mestizo adolescents.

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      Affiliations
      [1 ] Molecular Medicine Division, Centro de Investigación Biomédica de Occidente (CIBO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México. francisco.mendozac@imss.gob.mx
      Journal
      Arch. Med. Res.
      Archives of medical research
      1873-5487
      0188-4409
      Aug 2010
      : 41
      : 6
      21044752
      S0188-4409(10)00263-8
      10.1016/j.arcmed.2010.08.015
      Copyright © 2010 IMSS. Published by Elsevier Inc. All rights reserved.

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