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      Serum Insulin-Like Growth Factor Levels Do Not Predict Functional Recovery after Hospitalization in Nonagenarian Patients

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          Aim: To analyze the insulin-like growth factor 1 (IGF-1) serum levels in nonagenarian patients and to investigate the predictive capacity of this measure to assess the functional recovery of this population following hospitalization. Methods: We performed a prospective study in 60 consecutive nonagenarian patients admitted for medical or surgical diseases. We assessed IGF-1 serum levels and nutritional status. The functional status was assessed using the Barthel index. Thirty-four patients were reinvestigated 3 months after discharge from hospital. Results: The mean levels of IGF-1 were lower in nonagenarians than in younger patients. No relationship was found between IGF-1 levels and nutritional status. The decline in Barthel index values 3 months after discharge from hospital did not correlate with serum levels of IGF-1 on admission. Conclusion: IGF-1 serum levels in nonagenarian patients do not predict functional recovery after hospitalization.

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          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          08 May 2003
          : 59
          : 5
          : 249-253
          aGeriatric Unit, Internal Medicine Service, and bHormone and Genetic Unit, CSU de Bellvitge, L’Hospitalet de Llobregat, Barcelona, Spain
          70225 Horm Res 2003;59:249–253
          © 2003 S. Karger AG, Basel

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          Tables: 3, References: 22, Pages: 5
          Original Paper


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