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      Prevalencia de infección por helicobacter pylori en una población del Estado Nueva Esparta: Correlación Clínica, endoscopica y anatomopatológica

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          Abstract

          El Helicobacter pylori es un patógeno humano importante que infecta cerca de la mitad de la población mundial, la colonización de la mucosa gástrica resulta en el desarrollo de gastritis crónica, progresando a úlcera y cáncer. Objetivo: Determinar las características epidemiológicas, clínicas, hallazgos endoscópicos e histológicos en pacientes con infección por Helicobacter pylori en una población del estado Nueva Esparta. Materiales y Métodos: Se realizo un estudio retrospectivo recopilando los datos de las historias de los pacientes evaluados en la unidad de gastroenterología en la Clínica Popular "Nueva Esparta", la Asunción, Estado Nueva Esparta, con trastornos dispépticos que tenía Helicobcater pylori positivo en las biopsias, desde el mes de octubre del año 2006 a marzo del año 2007.Resultados: Se estudiaron 158 pacientes, la prevalencia para Helicobacter pylori fue de 82,1%, de los cuales 50 (31,64%) pertenecían al genero masculino y 108 (68,35%) al genero femenino, con edades entre 18 y 80 años. Evidenciándose la epigastralgia como el síntoma más relevante: 51,01%. En los hallazgos endoscópicos prevalece la gastritis erosiva en antro: 66,6%. En los hallazgos histológicos prevalece la gastritis crónica activa: 36,51%. Existe mayor prevalencia en el municipio Mariño: 25,32%. Conclusión: La infección por Helicobacter pylori en nuestra población es alta, relacionándose con trastornos dispépticos, disminuyendo de esta forma su calidad de vida.

          Translated abstract

          Helicobacter pylori is an important human pathogen that infects nearly half of the world´s population. Colonization of the gastric mucosa may result in the development of chronic gastritis with progressing to ulcer or cancer. Objective: To determine the epidemiological and clinical characteristics, endoscopic and histological findings in patients with Helicobacter pylori infection in a population of Nueva Esparta state. Materials And Methods: A retrospective study was done compiling the information in the files of patients evaluated at the gastroenterology unit in the Popular Clinic "Nueva Esparta", located in La Asuncion city, Nueva Esparta state, with dyspeptic disorders in the presence of helicobacter pylori in the biopsies, from October, 2006 to March, 2007. Results: 158 patients were studied, the prevalence for Helicobacter pylori was 82, 1 %, 50 male(31, 64 %) and 108 female patients (68,35%), with ages between 18 and 80 years old. Epigastric pain was the most relevant symptom: 51, 01 % of ptients .Erosive gastritis prevailed as the main endoscopic finding in: 66, 6 %. Chronic active gastritis in the biopsies represented: 36, 51 %. There is a higher prevalence at the Mariño District: 25, 32 %. Conclusion: Helicobacter pylori infection in our population is high and related with dyspeptic disorders, affecting our quality of life.

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          Unidentified curved bacilli on gastric epithelium in active chronic gastritis.

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            Helicobacter pylori and antimicrobial resistance: molecular mechanisms and clinical implications.

            Helicobacter pylori is an important human pathogen that colonises the stomach of about half of the world's population. The bacterium has now been accepted as the causative agent of several gastroduodenal disorders, ranging from chronic active gastritis and peptic ulcer disease to gastric cancer. The recognition of H pylori as a gastric pathogen has had a substantial effect on gastroenterological practice, since many untreatable gastroduodenal disorders with uncertain cause became curable infectious diseases. Treatment of H pylori infection results in ulcer healing and can reduce the risk of gastric cancer development. Although H pylori is susceptible to many antibiotics in vitro, only a few antibiotics can be used in vivo to cure the infection. The frequent indication for anti-H pylori therapy, together with the limited choice of antibiotics, has resulted in the development of antibiotic resistance in H pylori, which substantially impairs the treatment of H pylori-associated disorders. Antimicrobial resistance in H pylori is widespread, and although the prevalence of antimicrobial resistance shows regional variation per antibiotic, it can be as high as 95%. We focus on the treatment of H pylori infection and on the clinical relevance, mechanisms, and diagnosis of antimicrobial resistance.
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              Características clínicas y epidemiológicas de la infección por Helicobacter pylori en una población de los Andes Venezolanos

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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                gen
                Gen
                Gen
                Sociedad Venezolana de Gastroentereología (Caracas )
                0016-3503
                December 2008
                : 62
                : 4
                : 290-293
                Affiliations
                [1 ] Clínica Popular Nueva Esparta Venezuela
                [2 ] Hospital Militar tipo I Nelson Sayago Mora Venezuela
                [3 ] Clínica Popular Nueva Esparta Venezuela
                [4 ] Clínica Popular Nueva Esparta Venezuela
                Article
                S0016-35032008000400006
                d363f325-5231-4768-876b-5ebd0b581944

                http://creativecommons.org/licenses/by/4.0/

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                SciELO Venezuela

                Self URI (journal page): http://www.scielo.org.ve/scielo.php?script=sci_serial&pid=0016-3503&lng=en

                dispepsia,hallazgos histológicos y endoscópicos,histological and endoscopic finds,H pylori,dyspepsia

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