Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling.

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Abstract

To examine the potential anti-tumor activity of paeoniflorin in the human gastric carcinoma cell line MGC-803.

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Journal

Journal ID (iso-abbrev): World J. Gastroenterol.

Title: World journal of gastroenterology

Publisher: Baishideng Publishing Group Inc.

ISSN (Electronic): 2219-2840

ISSN (Print): 1007-9327

Publication date (Electronic): Jun 21 2015

Volume: 21

Issue: 23

Affiliations

[1 ] Yong-Bin Zheng, Gao-Chun Xiao, Shi-Lun Tong, Yu Ding, Qiu-Shuang Wang, Sheng-Bo Li, Zhi-Nan Hao, Department of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.

Article

DOI: 10.3748/wjg.v21.i23.7197

PMC ID: 4476881

PubMed ID: 26109806

SO-VID: d3b40b6a-19e3-43fc-910f-2303c0817885

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Keywords: Signal transducer and activator of transcription 3,Akt,Gastric cancer,MicroRNA-124,Paeoniflorin,Phosphatidylinositol 3-kinase

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Keywords: Signal transducer and activator of transcription 3, Akt, Gastric cancer, MicroRNA-124, Paeoniflorin, Phosphatidylinositol 3-kinase

Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling.

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