For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
18
views
15
references
 Top references
cited by
5
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      380
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: not found

      Developing a Comprehensive Pesticide Health Effects Tracking System for an Urban Setting: New York City’s Approach

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          In recent years, there have been substantial investments and improvements in federal and state surveillance systems to track the health effects from pesticide exposure. These surveillance systems help to identify risk factors for occupational exposure to pesticides, patterns in poisonings, clusters of disease, and populations at risk of exposure from pesticide use. Data from pesticide use registries and recent epidemiologic evidence pointing to health risks from urban residential pesticide use make a strong case for understanding better the sale, application, and use of pesticides in cities. In this article, we describe plans for the development of a pesticide tracking system for New York City that will help to elucidate where and why pesticides are used, potential risks to varied populations, and the health consequences of their use. The results of an inventory of data sources are presented along with a description of their relevance to pesticide tracking. We also discuss practical, logistical, and methodologic difficulties of linking multiple secondary data sources with different levels of person, place, and time descriptors.

          Related collections

          Most cited references15

          • Record: found
          • Abstract: found
          • Article: not found

          Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic population.

          Frederica Perera, Virginia Rauh, Wei-Yann Tsai … (2003)
          Inner-city, minority populations are high-risk groups for adverse birth outcomes and also are more likely to be exposed to environmental contaminants, including environmental tobacco smoke (ETS), polycyclic aromatic hydrocarbons (PAHs), and pesticides. In a sample of 263 nonsmoking African-American and Dominican women, we evaluated the effects on birth outcomes of prenatal exposure to airborne PAHs monitored during pregnancy by personal air sampling, along with ETS estimated by plasma cotinine, and an organophosphate pesticide (OP) estimated by plasma chlorpyrifos (CPF). Plasma CPF was used as a covariate because it was the most often detected in plasma and was highly correlated with other pesticides frequently detected in plasma. Among African Americans, high prenatal exposure to PAHs was associated with lower birth weight (p = 0.003) and smaller head circumference (p = 0.01) after adjusting for potential confounders. CPF was associated with decreased birth weight and birth length overall (p = 0.01 and p = 0.003, respectively) and with lower birth weight among African Americans (p = 0.04) and reduced birth length in Dominicans (p < 0.001), and was therefore included as a covariate in the model with PAH. After controlling for CPF, relationships between PAHs and birth outcomes were essentially unchanged. In this analysis, PAHs and CPF appear to be significant independent determinants of birth outcomes. Further analyses of pesticides will be carried out. Possible explanations of the failure to find a significant effect of PAHs in the Hispanic subsample are discussed. This study provides evidence that environmental pollutants at levels currently encountered in New York City adversely affect fetal development.
          Article 0 comments Cited 157 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Prenatal Insecticide Exposures and Birth Weight and Length among an Urban Minority Cohort

            Robin Whyatt, Virginia Rauh, Dana Barr … (2004)
            We reported previously that insecticide exposures were widespread among minority women in New York City during pregnancy and that levels of the organophosphate chlorpyrifos in umbilical cord plasma were inversely associated with birth weight and length. Here we expand analyses to include additional insecticides (the organophosphate diazinon and the carbamate propoxur), a larger sample size (n = 314 mother–newborn pairs), and insecticide measurements in maternal personal air during pregnancy as well as in umbilical cord plasma at delivery. Controlling for potential confounders, we found no association between maternal personal air insecticide levels and birth weight, length, or head circumference. For each log unit increase in cord plasma chlorpyrifos levels, birth weight decreased by 42.6 g [95% confidence interval (CI), −81.8 to −3.8, p = 0.03] and birth length decreased by 0.24 cm (95% CI, −0.47 to −0.01, p = 0.04). Combined measures of (ln)cord plasma chlorpyrifos and diazinon (adjusted for relative potency) were also inversely associated with birth weight and length (p 0.8). The propoxur metabolite 2-isopropoxyphenol in cord plasma was inversely associated with birth length, a finding of borderline significance (p = 0.05) after controlling for chlorpyrifos and diazinon. Results indicate that prenatal chlorpyrifos exposures have impaired fetal growth among this minority cohort and that diazinon exposures may have contributed to the effects. Findings support recent regulatory action to phase out residential uses of the insecticides.
            Article 0 comments Cited 102 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              In utero pesticide exposure, maternal paraoxonase activity, and head circumference.

              Gertrud S. Berkowitz, James Wetmur, Elena Birman-Deych … (2004)
              Although the use of pesticides in inner-city homes of the United States is of considerable magnitude, little is known about the potentially adverse health effects of such exposure. Recent animal data suggest that exposure to pesticides during pregnancy and early life may impair growth and neurodevelopment in the offspring. To investigate the relationship among prenatal pesticide exposure, paraoxonase (PON1) polymorphisms and enzyme activity, and infant growth and neurodevelopment, we are conducting a prospective, multiethnic cohort study of mothers and infants delivered at Mount Sinai Hospital in New York City. In this report we evaluate the effects of pesticide exposure on birth weight, length, head circumference, and gestational age among 404 births between May 1998 and May 2002. Pesticide exposure was assessed by a prenatal questionnaire administered to the mothers during the early third trimester as well as by analysis of maternal urinary pentachlorophenol levels and maternal metabolites of chlorpyrifos and pyrethroids. Neither the questionnaire data nor the pesticide metabolite levels were associated with any of the fetal growth indices or gestational age. However, when the level of maternal PON1 activity was taken into account, maternal levels of chlorpyrifos above the limit of detection coupled with low maternal PON1 activity were associated with a significant but small reduction in head circumference. In addition, maternal PON1 levels alone, but not PON1 genetic polymorphisms, were associated with reduced head size. Because small head size has been found to be predictive of subsequent cognitive ability, these data suggest that chlorpyrifos may have a detrimental effect on fetal neurodevelopment among mothers who exhibit low PON1 activity.
              Article 0 comments Cited 76 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Environ Health Perspect
                Title: Environmental Health Perspectives
                Publisher: National Institue of Environmental Health Sciences
                ISSN (Print): 0091-6765
                Publication date (Print): October 2004
                Publication date (Electronic): 3 August 2004
                Volume: 112
                Issue: 14
                Pages: 1419-1423
                Affiliations
                1New York City Department of Health and Mental Hygiene, Bureau of Environmental Disease Prevention, New York, New York, USA
                2Consultant, Williamstown, Massachusetts, USA
                Author notes
                Address correspondence to D.E. Kass, New York City Department of Health and Mental Hygiene, Environmental Public Health Tracking Program, 253 Broadway, CN-34C, New York, NY 10007 USA. Telephone: (212) 442-2638. Fax: (212) 676-2911. E-mail: dkass@health.nyc.gov

                This article is part of the mini-monograph “National Environmental Public Health Tracking,” which is sponsored by the Centers for Disease Control and Prevention (CDC).

                We gratefully acknowledge the guidance provided by members of the New York City Department of Health and Mental Hygiene Environmental Connections Advisory Panel.

                This work was generously supported by cooperative agreements U50/CCU223290 and U50/CCU222455 from CDC.

                This article was supported by an environmental public health tracking cooperative agreement from CDC. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of CDC.

                The authors declare they have no competing financial interests.

                Article
                Publisher ID: ehp0112-001419
                DOI: 10.1289/ehp.7149
                PMC ID: 1247571
                PubMed ID: 15471736
                SO-VID: d3c6710c-4fd0-4f74-b93b-b65cadf97044
                Copyright © This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original DOI.
                History
                Date received : 1 April 2004
                Date accepted : 3 August 2004
                Categories
                Subject: Mini-Monograph: Public Health Tracking
                Subject: Articles

                ScienceOpen disciplines: Public health
                Keywords: new york city,epidemiology,pest control,pesticide use,surveillance,poison control,data linkage
                Data availability:
                ScienceOpen disciplines: Public health
                Keywords: new york city, epidemiology, pest control, pesticide use, surveillance, poison control, data linkage

                Comments

                Comment on this article

                scite_

                Similar content380

                See all similar

                Cited by5

                See all cited by

                Most referenced authors148

                See all reference authors