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      Circulating tumor cells: liquid biopsy of cancer.

      Clinical chemistry
      American Association for Clinical Chemistry (AACC)

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          Abstract

          The detection and molecular characterization of circulating tumor cells (CTCs) are one of the most active areas of translational cancer research, with >400 clinical studies having included CTCs as a biomarker. The aims of research on CTCs include (a) estimation of the risk for metastatic relapse or metastatic progression (prognostic information), (b) stratification and real-time monitoring of therapies, (c) identification of therapeutic targets and resistance mechanisms, and (d) understanding metastasis development in cancer patients.

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          Journal
          23014601
          10.1373/clinchem.2012.194258

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