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      Validación por expertos del Índice de Distrés Peri-traumático relacionado con la Enfermedad por Coronavirus 2019 para su uso en el Perú Translated title: Expert validation of the COVID-2019 Peri-traumatic Distress Index for use in Peru

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          Abstract

          RESUMEN Objetivo: Efectuar una validación de contenido por expertos del Índice de Distrés Peri-traumático relacionado a COVID-19 (CPDI) para su uso en el Perú. Material y Métodos: El CPDI fue traducido al castellano y luego adaptado en una primera ronda de expertos. En una segunda ronda (n = 13), se evaluó la validez del contenido mediante el uso de la V de Aiken (V). Se calculó la V para cada ítem, así como para el instrumento en su conjunto (VTOT). Resultados : De los 24 ítems originales, solo un ítem (S7) presentó valores no significativos para validez de contenido, razón por la que fue eliminado. La escala con 23 ítems no presentó alteraciones en el cálculo de la VTOT. Conclusiones : Sobre la base de su validez de contenido, el CPDI en castellano es adecuado para su aplicación en la población peruana. Quedan por definirse las características psicométricas así como la modificación propuesta del instrumento, mediante estudios cuantitativos en torno a la validez del constructo.

          Translated abstract

          SUMMARY Objectives : To perform an expert validation study of COVID-19 Peritraumatic Distress Index (CPDI) for its eventual use in Perú. Material and Methods: In a first round by experts, the CPDI was translated into Spanish and then adapted. In a second round, (n = 13), the content validity was evaluated by using Aiken’s V (V). The V was calculated for each item, as well as for the whole instrument (VTOT). Results : Of the 24 original items, only one (S7) presented non-significant values for content validity, reason for which it was removed. The final 23-items scale did not present any alterations for the VTOT calculation. Conclusions : On the basis of its adequate content validity, the Spanish version of CPDI is suitable for its application in the Peruvian population. The psychometric characteristics of the instrument, as well as its proposed modification remain to be defined through quantitative studies of the construct validity.

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          Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

          Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described. Methods In this retrospective, multicentre cohort study, we included all adult inpatients (≥18 years old) with laboratory-confirmed COVID-19 from Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) who had been discharged or had died by Jan 31, 2020. Demographic, clinical, treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records and compared between survivors and non-survivors. We used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death. Findings 191 patients (135 from Jinyintan Hospital and 56 from Wuhan Pulmonary Hospital) were included in this study, of whom 137 were discharged and 54 died in hospital. 91 (48%) patients had a comorbidity, with hypertension being the most common (58 [30%] patients), followed by diabetes (36 [19%] patients) and coronary heart disease (15 [8%] patients). Multivariable regression showed increasing odds of in-hospital death associated with older age (odds ratio 1·10, 95% CI 1·03–1·17, per year increase; p=0·0043), higher Sequential Organ Failure Assessment (SOFA) score (5·65, 2·61–12·23; p<0·0001), and d-dimer greater than 1 μg/mL (18·42, 2·64–128·55; p=0·0033) on admission. Median duration of viral shedding was 20·0 days (IQR 17·0–24·0) in survivors, but SARS-CoV-2 was detectable until death in non-survivors. The longest observed duration of viral shedding in survivors was 37 days. Interpretation The potential risk factors of older age, high SOFA score, and d-dimer greater than 1 μg/mL could help clinicians to identify patients with poor prognosis at an early stage. Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future. Funding Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences; National Science Grant for Distinguished Young Scholars; National Key Research and Development Program of China; The Beijing Science and Technology Project; and Major Projects of National Science and Technology on New Drug Creation and Development.
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            A nationwide survey of psychological distress among Chinese people in the COVID-19 epidemic: implications and policy recommendations

            The Coronavirus Disease 2019 (COVID-19) epidemic emerged in Wuhan, China, spread nationwide and then onto half a dozen other countries between December 2019 and early 2020. The implementation of unprecedented strict quarantine measures in China has kept a large number of people in isolation and affected many aspects of people’s lives. It has also triggered a wide variety of psychological problems, such as panic disorder, anxiety and depression. This study is the first nationwide large-scale survey of psychological distress in the general population of China during the COVID-19 epidemic.
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              Propriedades psicométricas na avaliação de instrumentos: avaliação da confiabilidade e da validade

              Resumo Instrumentos de medida desempenham um importante papel na pesquisa, na prática clínica e na avaliação de saúde. Estudos sobre a qualidade desses instrumentos fornecem evidências de como as propriedades de medida foram avaliadas, auxiliando o pesquisador na escolha da melhor ferramenta para utilização. A confiabilidade e a validade são consideradas as principais propriedades de medida de tais instrumentos. Confiabilidade é a capacidade em reproduzir um resultado de forma consistente, no tempo e no espaço. Validade refere-se à propriedade de um instrumento medir exatamente o que se propõe. Neste artigo são apresentados, discutidos e exemplificados os principais critérios e testes estatísticos empregados na avaliação da confiabilidade (estabilidade, consistência interna e equivalência) e validade (conteúdo, critério e construto) de instrumentos. A avaliação das propriedades de medida de instrumentos é útil para subsidiar a seleção de instrumentos válidos e confiáveis, de modo a assegurar a qualidade dos resultados dos estudos.
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                Author and article information

                Journal
                rnp
                Revista de Neuro-Psiquiatría
                Rev Neuropsiquiatr
                Universidad Peruana Cayetano Heredia. Facultad de Medicina (Lima, , Peru )
                0034-8597
                October 2020
                : 83
                : 4
                : 228-235
                Affiliations
                [2] Lima orgnameHospital Nacional Cayetano Heredia orgdiv1Servicio de Neuropsiquiatría Perú
                [1] Giessen orgnameUniversidad Justus-Liebig orgdiv1Centro de Psiquiatría orgdiv2Centro de Neurociencias Alemania
                Article
                S0034-85972020000400228 S0034-8597(20)08300400228
                10.20453/rnp.v83i4.3888
                d404245f-7ab1-461a-8214-e8b3f47a3ef1

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 08 May 2020
                : 05 December 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 16, Pages: 8
                Product

                SciELO Peru

                Categories
                Artículos originales

                salud mental.,estrés emocional,estudio de validación,pandemias,COVID-19,mental health.,psychological distress,validation studies,Pandemics

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