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      Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury

      Free Radical Biology and Medicine

      Elsevier BV

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          Most cited references 148

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          A simple fluorometric assay for lipoperoxide in blood plasma.

           K Yagi (1976)
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            Assay for lipid peroxidation in animal tissueby thiobarbituric acid reaction

             H Ohkawa,  N Onishi,  K Yagi (1979)
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              The measurement and mechanism of lipid peroxidation in biological systems.

              The basic chemistry of the propagation of lipid peroxidation reactions has been known for years, but the mechanism of initiation of this process in biological membrane systems is still uncertain. Currently available assays for measuring peroxidation are reviewed--the more specific the assay used, the less peroxide is found in healthy human tissues and body fluids. Lipid peroxidation can arise as a consequence of tissue injury in many disease states and may sometimes contribute significantly to worsening the tissue injury.
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                Author and article information

                Journal
                Free Radical Biology and Medicine
                Free Radical Biology and Medicine
                Elsevier BV
                08915849
                January 1990
                January 1990
                : 9
                : 6
                : 515-540
                Article
                10.1016/0891-5849(90)90131-2
                © 1990

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