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      French lyophilized plasma versus fresh frozen plasma for the initial management of trauma-induced coagulopathy: a randomized open-label trial.

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          Abstract

          Essentials An immediate supply of plasma in case of trauma-induced coagulopathy is required. The Traucc trial compared French Lyophilised Plasma (FLyP) and Fresh Frozen Plasma (FFP). FLyP achieved higher fibrinogen concentrations compared with FFP. FLyP led to a more rapid coagulopathy improvement than FFP.

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          Author and article information

          Journal
          J. Thromb. Haemost.
          Journal of thrombosis and haemostasis : JTH
          Wiley
          1538-7836
          1538-7836
          Mar 2018
          : 16
          : 3
          Affiliations
          [1 ] CHU de Lille, Pôle d'Anesthésie-Réanimation, Lille, France.
          [2 ] CHU Lille, Pôle de l'Urgence, Lille, France.
          [3 ] Service d'Anesthésie-Réanimation, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.
          [4 ] NSERM, UMR-S1140, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
          [5 ] Université Lille, CHU Lille, EA 2694 - Santé Publique: Épidémiologie et Qualité des Soins, Lille, France.
          [6 ] Université Lille, EA 7366, Lille, France.
          [7 ] CHU de Lille, Institut d'Hématologie-Transfusion, Lille, France.
          [8 ] EFS Hauts de France, Lille, France.
          [9 ] Centre de Transfusion Sanguine des Armées, Clamart, France.
          [10 ] Université Lille, Inserm, CHU Lille, U1011 - EGID, Lille, France.
          Article
          10.1111/jth.13929
          29274254
          d471cf3e-5901-4735-9e10-f898b6c6c58d
          History

          plasma transfusion,blood transfusion,coagulopathy,fibrinogen,trauma

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