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      Efficacy of a two-test protocol for achieving a therapeutic response to clopidogrel prior to elective endovascular intracranial aneurysm treatment and an 'induced' postoperative hyper-response.

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          Abstract

          Variable response to clopidogrel can impact perioperative risk in elective endovascular intracranial aneurysm treatment. The present study aims to determine the efficacy of a two-test protocol in reaching in-range preoperative P2Y12 reaction units (PRU) of 60-240 and the rate of postoperative conversion to hyper-response.

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          Author and article information

          Journal
          J Neurointerv Surg
          Journal of neurointerventional surgery
          BMJ
          1759-8486
          1759-8478
          Aug 2017
          : 9
          : 8
          Affiliations
          [1 ] Section of Neurointerventional Radiology, Neuroscience Institute, Abbott Northwestern Hospital, Consulting Radiologists Ltd, Minneapolis, Minnesota, USA.
          [2 ] Department of Critical Care, Neuroscience Institute, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA.
          Article
          neurintsurg-2016-012409
          10.1136/neurintsurg-2016-012409
          27436404

          Intervention, Platelets, Aneurysm, Drug, Pharmacology

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