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      Calcium Silicate-Based Experimental Sealers: Physicochemical Properties Evaluation

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          Abstract

          Abstract The aim of this study was to evaluate physicochemical properties of calcium silicate-based experimental (CS) endodontic sealers, developed using two different vehicles: polyethylene glycol (PG) (CS-PG) or polyethylene glycol associated to chitosan hydrogel (CS-PGCH). TotalFill BC Sealer (TF) and AH Plus (AHP) were evaluated for comparison. Setting time, flow, radiopacity, pH, solubility and volumetric change were analyzed. Data were submitted to ANOVA and Tukey tests with 5% significance level. The CS-PGCH had significantly greater setting time. CS-PG flow was similar to AHP. CS-PG had higher radiopacity than CS-PGCH. Calcium silicate-based sealers presented alkaline pH in all periods. CS-PGCH presented higher solubility in comparison with CS-PG. The volumetric change of CS-PG was similar to TF after 7 days, and to AHP after 30 days. CS-PG presented proper setting time, radiopacity, flow and pH, besides low volumetric change, showing better results than CS-PGCH, and potential for clinical application.

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          Most cited references44

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          Physical properties of 5 root canal sealers.

          The aim of this study was to evaluate the pH change, viscosity and other physical properties of 2 novel root canal sealers (MTA Fillapex and Endosequence BC) in comparison with 2 epoxy resin-based sealers (AH Plus and ThermaSeal), a silicone-based sealer (GuttaFlow), and a zinc oxide-eugenol-based sealer (Pulp Canal Sealer).
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            Evaluation of radiopacity, pH, release of calcium ions, and flow of a bioceramic root canal sealer.

            The aim of the present study was to evaluate the physicochemical properties of a bioceramic root canal sealer, Endosequence BC Sealer. Radiopacity, pH, release of calcium ions (Ca(2+)), and flow were analyzed, and the results were compared with AH Plus cement.
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              Calcium silicate bioactive cements: Biological perspectives and clinical applications.

              To introduce and to examine the research progress and the investigation on hydraulic calcium silicate cements (HCSCs), well-known as MTA (mineral trioxide aggregate). This review paper introduces the most important investigations of the last 20 years and analyze their impact on HCSCs use in clinical application. HCSCs were developed more than 20 years ago. Their composition is largely based on Portland cement components (di- and tri-calcium silicate, Al- and Fe-silicate). They have important properties such as the ability to set and to seal in moist and blood-contaminated environments, biocompatibility, adequate mechanical properties, etc. Their principal limitations are long setting time, low radiopacity and difficult handling. New HCSCs-based materials containing additional components (setting modulators, radiopacifying agents, drugs, etc.) have since been introduced and have received a considerable attention from laboratory researchers for their biological and translational characteristics and from clinicians for their innovative properties. HCSCs upregulate the differentiation of osteoblast, fibroblasts, cementoblasts, odontoblasts, pulp cells and many stem cells. They can induce the chemical formation of a calcium phosphate/apatite coating when immersed in biological fluids. These properties have led to a growing series of innovative clinical applications such as root-end filling, pulp capping and scaffolds for pulp regeneration, root canal sealer, etc. The capacity of HCSCs to promote calcium-phosphate deposit suggests their use for dentin remineralization and tissue regeneration. Several in vitro studies, animal tests and clinical studies confirmed their ability to nucleate apatite and remineralize and to induce the formation of (new) mineralized tissues. HCSCs play a critical role in developing a new approach for pulp and bone regeneration, dentin remineralization, and bone/cementum tissue healing. Investigations of the next generation HCSCs for "Regenerative Dentistry" will guide their clinical evolution. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
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                Author and article information

                Journal
                mr
                Materials Research
                Mat. Res.
                ABM, ABC, ABPol (São Carlos, SP, Brazil )
                1516-1439
                1980-5373
                2021
                : 24
                : 1
                : e20200243
                Affiliations
                [01] Araraquara São Paulo orgnameUniversidade Estadual Paulista orgdiv1Faculdade de Odontologia de Araraquara orgdiv2Departamento de Odontologia Restauradora Brazil
                Article
                S1516-14392021000100212 S1516-1439(21)02400100212
                10.1590/1980-5373-mr-2020-0243
                d4d42cec-686c-401f-abee-afd908dfbceb

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 04 June 2020
                : 11 October 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 44, Pages: 0
                Product

                SciELO Brazil

                Categories
                Articles

                X-Ray Microtomography,Physical Properties,: Biocompatible Materials,Dental Materials,Calcium Silicate

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