Kelsey J. Yamada:
ORCID: http://orcid.org/0000-0003-1071-8836
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Writing – original draftRole: Writing – review & editing
Cortney E. Heim: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – review & editing
Xinyuan Xi:
ORCID: http://orcid.org/0000-0003-3272-1761
Role: MethodologyRole: Writing – review & editing
Kuldeep S. Attri: Role: Formal analysisRole: InvestigationRole: Writing – review & editing
Dezhen Wang: Role: InvestigationRole: Writing – review & editing
Wenting Zhang:
ORCID: http://orcid.org/0000-0002-6406-5220
Role: MethodologyRole: Writing – review & editing
Pankaj K. Singh: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – review
& editing
Tatiana K. Bronich:
ORCID: http://orcid.org/0000-0003-4192-8422
Role: ConceptualizationRole: Funding acquisitionRole: MethodologyRole: Writing – review
& editing
Tammy Kielian:
ORCID: http://orcid.org/0000-0001-7624-670X
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: Project
administrationRole: SupervisionRole: Writing – original draftRole: Writing – review
& editing
Andreas Peschel: Role: Editor
Journal ID (nlm-ta): PLoS Pathog
Journal ID (iso-abbrev): PLoS Pathog
Journal ID (publisher-id): plos
Journal ID (pmc): plospath
Title:
PLoS Pathogens
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7366
ISSN
(Electronic):
1553-7374
Publication date
(Electronic):
6
March
2020
Publication date Collection:
March
2020
Volume: 16
Issue: 3
Electronic Location Identifier: e1008354
Affiliations
[1
]
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha,
Nebraska, United States of America
[2
]
Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha,
Nebraska, United States of America
[3
]
Eppley Institute, University of Nebraska Medical Center, Omaha, Nebraska, United States
of America
University of Tubingen, GERMANY
Author notes
I have read the journal's policy and the authors of this manuscript have the following
competing interests: A provisional patent has been filed with the US Patent and Trademark
Office covering the application of nanoparticle targeting of monocyte metabolism for
the treatment of biofilm-associated infections (62/730,229; TK, TKB, KJY, XX).
Author information
Article
Publisher ID:
PPATHOGENS-D-19-01259
DOI: 10.1371/journal.ppat.1008354
PMC ID: 7080272
PubMed ID: 32142554
SO-VID: d5501c7f-400f-4102-8eff-930b67c6c015
Copyright © © 2020 Yamada et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000060, National Institute of Allergy and Infectious Diseases;
Award ID: P01 AI083211
Award Recipient
:
ORCID: http://orcid.org/0000-0001-7624-670X
Tammy Kielian
Funded by: funder-id http://dx.doi.org/10.13039/100000054, National Cancer Institute;
Award ID: U01 CA198910
Award Recipient
:
ORCID: http://orcid.org/0000-0003-4192-8422
Tatiana K. Bronich
Funded by: funder-id http://dx.doi.org/10.13039/100000057, National Institute of General Medical Sciences;
Award ID: P30GM127200
Award Recipient
:
ORCID: http://orcid.org/0000-0003-4192-8422
Tatiana K. Bronich
This work was supported by the National Institutes of Health/National Institute of
Allergy and Infectious Disease grant P01 AI083211 (Project 4 to TK), a UNMC Graduate
Studies Fellowship (to KJY) and U01 CA198910 and P30GM127200 (to TKB). The UNMC DNA
Sequencing Core receives partial support from the National Institute for General Medical
Science (NIGMS; INBRE - P20GM103427-14 and COBRE - 1P30GM110768-01). Both the UNMC
DNA Sequencing and Flow Cytometry Research Cores receive support from The Fred & Pamela
Buffett Cancer Center Support Grant (P30CA036727). The funders had no role in study
design, data collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Engineering and Technology
Subject:
Nanotechnology
Subject:
Nanoparticles
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Staphylococcus
Subject:
Staphylococcus Aureus
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Staphylococcus
Subject:
Staphylococcus Aureus
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Staphylococcus
Subject:
Staphylococcus Aureus
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Bacteriology
Subject:
Bacterial Biofilms
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Biofilms
Subject:
Bacterial Biofilms
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drugs
Subject:
Antimicrobials
Subject:
Antibiotics
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Control
Subject:
Antimicrobials
Subject:
Antibiotics
Subject:
Biology and Life Sciences
Subject:
Bioengineering
Subject:
Biotechnology
Subject:
Bionanotechnology
Subject:
Engineering and Technology
Subject:
Bioengineering
Subject:
Biotechnology
Subject:
Bionanotechnology
Subject:
Engineering and Technology
Subject:
Nanotechnology
Subject:
Bionanotechnology
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Metabolism
Subject:
Metabolites