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      IgG4-Related Ophthalmic Disease: Pooling of Published Cases and Literature Review.

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          Abstract

          In recent years, IgG4-related ophthalmic disease (IgG4-ROD) has emerged as a common cause of orbital inflammation, accounting for a substantial proportion of idiopathic orbital inflammation and lymphoid hyperplasia. The last pooled analysis of published cases was conducted in 2012, but a large number of new cases have been added to the literature since then. In this review, we present the demographic, clinical, histological, and treatment data for 172 published cases of biopsy-confirmed IgG4-ROD. Results are accompanied by a review of the relevant literature.

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          Author and article information

          Journal
          Curr Allergy Asthma Rep
          Current allergy and asthma reports
          Springer Nature
          1534-6315
          1529-7322
          Jun 2015
          : 15
          : 6
          Affiliations
          [1 ] South Australian Institute of Ophthalmology, University of Adelaide, Level 8, East Wing, Royal Adelaide Hospital, Adelaide, SA, 5000, Australia, albert.wu3@gmail.com.
          Article
          10.1007/s11882-015-0530-4
          26141575
          d5648d8f-38d2-4fe1-beee-935263c474ed
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