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      Penetrating keratoplasty and glaucoma.

      Survey of Ophthalmology
      Alkylating Agents, administration & dosage, Diagnosis, Differential, Glaucoma, diagnosis, epidemiology, etiology, therapy, Glaucoma Drainage Implants, Humans, Incidence, Intraocular Pressure, physiology, Keratoplasty, Penetrating, adverse effects, Mitomycin, Ophthalmic Solutions, Prognosis, Refractive Surgical Procedures, Risk Factors, Trabeculectomy

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          Abstract

          Glaucoma remains the leading cause of blindness after penetrating keratoplasty. Post-keratoplasty glaucoma was originally described in 1969, and its management is still controversial. Recent developments in management include newer classes of drugs, surgical procedures, such as trabeculectomy with mitomycin-C, implantation of glaucoma drainage devices, and cyclodestructive procedures with Nd: YAG and diode lasers. However, the risk of graft failure continues to be high with all surgical procedures.

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