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Morphometric MRI analysis enhances visualization of cortical tubers in tuberous sclerosis
Patrick M. House ,
Brigitte Holst ,
Matthias Lindenau ,
Berthold Voges ,
Bernhard Kohl ,
Tobias Martens ,
Michael Lanz ,
Stefan Stodieck ,
Hans-Jürgen Huppertz
November 2015
November 2015
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Abstract
Focal cortical dysplasias (FCD) type IIb and cortical tubers in tuberous sclerosis
complex (TSC) are histopathologically similar and are both epileptogenic lesions frequently
causing pharmacoresistant epilepsies. Morphometric analysis of T1- and T2-weighted
MRI volume data sets can enhance visualization of FCD. Here, we retrospectively investigated
whether morphometric MRI analysis is of equal benefit for visualizing cortical tubers.