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      A Review on the Modification of Polysaccharide Through Graft Copolymerization for Various Potential Applications

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          Abstract

          Introduction:

          Graft copolymerization is one of the most promising technique uses to modify the properties of naturally available polymers with a minimum loss in their native characteristics.

          Methods and Materials:

          Graft copolymerization is a very significant technique to add hybrid properties in backbone of polymers. The grafting generally initiated through the formation of free radical centers on the polymer backbone as well as monomer.

          Results:

          Grafted polysaccharides have various applications in different important scientific areas such as drug delivery, pharmaceutical field, plastic industry, waste water treatment, tannery effluent treatment, textile industry, agriculture area, etc. all of this fascinated us to summarize the major research articles over the last two decades outlining different methods of grafting, surface modification, graft copolymerization of synthetic and natural polymers.

          Conclusion:

          Various redox initiator systems viz. Ceric ammonium nitrate, per sulfate, Irradiation, FAS-H 2O 2 etc. is also explored for grafting of vinyl through conventional and non-conventional techniques.

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          Most cited references68

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          Recent developments in polysaccharide-based materials used as adsorbents in wastewater treatment

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            Dielectric parameters relevant to microwave dielectric heating

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              Psyllium as therapeutic and drug delivery agent.

              There is no doubt that fibers, in particular viscous dietary fibers, have positive effects on human health, both in the prevention and in treatment of chronic diseases. Dietary fibers from psyllium have been used extensively both as pharmacological supplements, food ingredients, in processed food to aid weight control, to regulation of glucose control for diabetic patients and reducing serum lipid levels in hyperlipidemics. Keeping in view, the pharmacological importance of psyllium polysaccharide and its gel-forming nature, this article discusses the therapeutic value of psyllium for the treatment of constipation, diarrhea, irritable bowel syndrome, inflammatory bowel disease-ulcerative colitis, colon cancer, diabetes and hypercholesterolemia and exploitation of psyllium for developing drug delivery systems.
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                Author and article information

                Journal
                Open Med Chem J
                Open Med Chem J
                TOMCJ
                The Open Medicinal Chemistry Journal
                Bentham Open
                1874-1045
                26 September 2017
                2017
                : 11
                : 109-126
                Affiliations
                [1 ]Department of Applied Chemistry, MJP Rohilkhand University, Bareilly – 243006(U.P.), India
                [2 ]Department of Applied Chemistry, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Rae Bareli Road, Lucknow 226025, India
                [3 ]Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Rae Bareli Road, Lucknow 226025, India
                Author notes
                [* ]Address correspondence to this authors at the Department of Applied Chemistry, MJP Rohilkhand University, Bareilly – 243006(U.P.), India; Tel: +9412602921; E-mail: pramendra2002@ 123456gmail.com
                Article
                TOMCJ-11-109
                10.2174/1874104501711010109
                5676014
                d5d8b672-cf84-47e3-a31b-7475962f6913
                © 2017 Kumar et al.

                This is an open access article distributed under the terms of the Creative Commons Attribution 4. 0 International Public License (CC-BY 4. 0), a copy of which is available at: https://creativecommons. org/licenses/by/4. 0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 16 March 2017
                : 20 August 2017
                : 23 August 2017
                Categories
                Article

                Pharmaceutical chemistry
                polysaccharides,grafting,copolymer,initiator
                Pharmaceutical chemistry
                polysaccharides, grafting, copolymer, initiator

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