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      COVID-19 con afectación cardiovascular. Reporte de un caso Translated title: COVID-19 with cardiovascular involvement. Case report Translated title: COVID-19 com envolvimento cardiovascular. Relato de um caso

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Resumen: Estamos transitando el inicio de la pandemia COVID-19 por el nuevo coronavirus SARS-CoV-2. Se ha reconocido que la forma de presentación puede ser con síntomas de la esfera cardiovascular. Reportamos el primer caso de un paciente ingresado a terapia intensiva con COVID-19 en Uruguay, quien se presentó al ingreso con sintomatología cardiovascular.

          Translated abstract

          Summary: We are transiting the onset of the COVID-19 pandemic caused by the new coronavirus SARS-CoV-2. It has been recognized that the form of presentation may be with cardiovascular symptoms. We report the first case of a patient admitted to intensive care affected with COVID-19 in Uruguay, who was admitted with cardiovascular symptoms.

          Translated abstract

          Resumo: Estamos no início da pandemia de COVID-19 causada pelo novo coronavírus SARS-CoV-2. Foi reconhecido que a forma de apresentação pode estar com sintomas cardiovasculares. Relatamos o primeiro caso de um paciente admitido em terapia intensiva afetada pelo COVID-19 no Uruguai, que foi admitido com sintomas cardiovasculares.

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          Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

          Chaolin Huang, Yeming Wang, Xingwang Li … (2020)
          Summary Background A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). We report the epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of these patients. Methods All patients with suspected 2019-nCoV were admitted to a designated hospital in Wuhan. We prospectively collected and analysed data on patients with laboratory-confirmed 2019-nCoV infection by real-time RT-PCR and next-generation sequencing. Data were obtained with standardised data collection forms shared by WHO and the International Severe Acute Respiratory and Emerging Infection Consortium from electronic medical records. Researchers also directly communicated with patients or their families to ascertain epidemiological and symptom data. Outcomes were also compared between patients who had been admitted to the intensive care unit (ICU) and those who had not. Findings By Jan 2, 2020, 41 admitted hospital patients had been identified as having laboratory-confirmed 2019-nCoV infection. Most of the infected patients were men (30 [73%] of 41); less than half had underlying diseases (13 [32%]), including diabetes (eight [20%]), hypertension (six [15%]), and cardiovascular disease (six [15%]). Median age was 49·0 years (IQR 41·0–58·0). 27 (66%) of 41 patients had been exposed to Huanan seafood market. One family cluster was found. Common symptoms at onset of illness were fever (40 [98%] of 41 patients), cough (31 [76%]), and myalgia or fatigue (18 [44%]); less common symptoms were sputum production (11 [28%] of 39), headache (three [8%] of 38), haemoptysis (two [5%] of 39), and diarrhoea (one [3%] of 38). Dyspnoea developed in 22 (55%) of 40 patients (median time from illness onset to dyspnoea 8·0 days [IQR 5·0–13·0]). 26 (63%) of 41 patients had lymphopenia. All 41 patients had pneumonia with abnormal findings on chest CT. Complications included acute respiratory distress syndrome (12 [29%]), RNAaemia (six [15%]), acute cardiac injury (five [12%]) and secondary infection (four [10%]). 13 (32%) patients were admitted to an ICU and six (15%) died. Compared with non-ICU patients, ICU patients had higher plasma levels of IL2, IL7, IL10, GSCF, IP10, MCP1, MIP1A, and TNFα. Interpretation The 2019-nCoV infection caused clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus and was associated with ICU admission and high mortality. Major gaps in our knowledge of the origin, epidemiology, duration of human transmission, and clinical spectrum of disease need fulfilment by future studies. Funding Ministry of Science and Technology, Chinese Academy of Medical Sciences, National Natural Science Foundation of China, and Beijing Municipal Science and Technology Commission.
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            Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study

            Nanshan Chen, Min Zhou, Xuan Dong … (2022)
            Summary Background In December, 2019, a pneumonia associated with the 2019 novel coronavirus (2019-nCoV) emerged in Wuhan, China. We aimed to further clarify the epidemiological and clinical characteristics of 2019-nCoV pneumonia. Methods In this retrospective, single-centre study, we included all confirmed cases of 2019-nCoV in Wuhan Jinyintan Hospital from Jan 1 to Jan 20, 2020. Cases were confirmed by real-time RT-PCR and were analysed for epidemiological, demographic, clinical, and radiological features and laboratory data. Outcomes were followed up until Jan 25, 2020. Findings Of the 99 patients with 2019-nCoV pneumonia, 49 (49%) had a history of exposure to the Huanan seafood market. The average age of the patients was 55·5 years (SD 13·1), including 67 men and 32 women. 2019-nCoV was detected in all patients by real-time RT-PCR. 50 (51%) patients had chronic diseases. Patients had clinical manifestations of fever (82 [83%] patients), cough (81 [82%] patients), shortness of breath (31 [31%] patients), muscle ache (11 [11%] patients), confusion (nine [9%] patients), headache (eight [8%] patients), sore throat (five [5%] patients), rhinorrhoea (four [4%] patients), chest pain (two [2%] patients), diarrhoea (two [2%] patients), and nausea and vomiting (one [1%] patient). According to imaging examination, 74 (75%) patients showed bilateral pneumonia, 14 (14%) patients showed multiple mottling and ground-glass opacity, and one (1%) patient had pneumothorax. 17 (17%) patients developed acute respiratory distress syndrome and, among them, 11 (11%) patients worsened in a short period of time and died of multiple organ failure. Interpretation The 2019-nCoV infection was of clustering onset, is more likely to affect older males with comorbidities, and can result in severe and even fatal respiratory diseases such as acute respiratory distress syndrome. In general, characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia. Further investigation is needed to explore the applicability of the MuLBSTA score in predicting the risk of mortality in 2019-nCoV infection. Funding National Key R&D Program of China.
            Article 0 comments Cited 9324 times – based on 0 reviews     Review now
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              Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention

              Zunyou Wu, Jennifer M. McGoogan (2020)
              Article 0 comments Cited 8349 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (publisher-id): ruc
                Title: Revista Uruguaya de Cardiología
                Abbreviated Title: Rev.Urug.Cardiol.
                Publisher: Sociedad Uruguaya de Cardiología (Montevideo, , Uruguay )
                ISSN (Print): 0797-0048
                ISSN (Electronic): 1688-0420
                Publication date (Print and electronic): 2020
                Volume: 35
                Issue: 2
                Pages: 256-262
                Affiliations
                [2] Montevideo orgnameAsociación Española Uruguay
                [1] Montevideo orgnameInstituto Nacional de Cirugía Cardíaca Uruguay ampiblu@ 123456gmail.com
                Article
                Publisher ID: S1688-04202020000200256 Publisher ID: S1688-0420(20)03500200256
                DOI: 10.29277/cardio.35.2.17
                SO-VID: d5e7b460-081f-4f5b-9ab5-e2830ed35db2
                License:

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                Date accepted : 14 April 2020
                Date received : 01 April 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 8, Pages: 7
                Product

                SciELO Uruguay

                Categories
                Subject: Cartas científicas

                Keywords: SARS-COV-2,COVID-19,Cardiologia,Cardiología,Cardiology
                Data availability:
                Keywords: SARS-COV-2, COVID-19, Cardiologia, Cardiología, Cardiology

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