18
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      A Positive Affective Neuroendocrinology Approach to Reward and Behavioral Dysregulation

      review-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Emerging lines of research suggest that both testosterone and maladaptive reward processing can modulate behavioral dysregulation. Yet, to date, no integrative account has been provided that systematically explains neuroendocrine function, dysregulation of reward, and behavioral dysregulation in a unified perspective. This is particularly important given specific neuroendocrine systems are potential mechanisms underlying and giving rise to reward-relevant behaviors. In this review, we propose a forward-thinking approach to study the mechanisms of reward and behavioral dysregulation from a positive affective neuroendocrinology (PANE) perspective. This approach holds that testosterone increases reward processing and motivation, which increase the likelihood of behavioral dysregulation. Additionally, the PANE framework holds that reward processing mediates the effects of testosterone on behavioral dysregulation. We also explore sources of potential sex differences and the roles of age, cortisol, and individual differences within the PANE framework. Finally, we discuss future prospects for research questions and methodology in the emerging field of affective neuroendocrinology.

          Related collections

          Most cited references204

          • Record: found
          • Abstract: not found
          • Article: not found

          Gender differences in risk taking: A meta-analysis.

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Self-control in decision-making involves modulation of the vmPFC valuation system.

            Every day, individuals make dozens of choices between an alternative with higher overall value and a more tempting but ultimately inferior option. Optimal decision-making requires self-control. We propose two hypotheses about the neurobiology of self-control: (i) Goal-directed decisions have their basis in a common value signal encoded in ventromedial prefrontal cortex (vmPFC), and (ii) exercising self-control involves the modulation of this value signal by dorsolateral prefrontal cortex (DLPFC). We used functional magnetic resonance imaging to monitor brain activity while dieters engaged in real decisions about food consumption. Activity in vmPFC was correlated with goal values regardless of the amount of self-control. It incorporated both taste and health in self-controllers but only taste in non-self-controllers. Activity in DLPFC increased when subjects exercised self-control and correlated with activity in vmPFC.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Impulse and Self-Control From a Dual-Systems Perspective.

              Though human beings embody a unique ability for planned behavior, they also often act impulsively. This insight may be important for the study of self-control situations in which people are torn between their long-term goals to restrain behavior and their immediate impulses that promise hedonic fulfillment. In the present article, we outline a dual-systems perspective of impulse and self-control and suggest a framework for the prediction of self-control outcomes. This framework combines three elements that, considered jointly, may enable a more precise prediction of self-control outcomes than they do when studied in isolation: impulsive precursors of behavior, reflective precursors, and situational or dispositional boundary conditions. The theoretical and practical utility of such an approach is demonstrated by drawing on recent evidence from several domains of self-control such as eating, drinking, and sexual behavior.
                Bookmark

                Author and article information

                Contributors
                Journal
                Front Psychiatry
                Front Psychiatry
                Front. Psychiatry
                Frontiers in Psychiatry
                Frontiers Media S.A.
                1664-0640
                02 July 2015
                2015
                : 6
                : 93
                Affiliations
                [1] 1Department of Psychology and Neuroscience, University of Colorado Boulder , Boulder, CO, USA
                [2] 2Department of Psychology, University of Oregon , Eugene, OR, USA
                Author notes

                Edited by: Miriam Melis, University of Cagliari, Italy

                Reviewed by: Liangsuo Ma, University of Texas Health Science Center at Houston, USA; Kesong Hu, Cornell University, USA

                *Correspondence: Pranjal H. Mehta, Department of Psychology, 1227 University of Oregon, Eugene, OR 97403, USA, mehta@ 123456uoregon.edu

                Specialty section: This article was submitted to Addictive Disorders and Behavioral Dyscontrol, a section of the journal Frontiers in Psychiatry

                Article
                10.3389/fpsyt.2015.00093
                4489099
                d5effb7d-ad02-48a9-93fc-08e19d4a872f
                Copyright © 2015 Welker, Gruber and Mehta.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 14 March 2015
                : 11 June 2015
                Page count
                Figures: 2, Tables: 0, Equations: 0, References: 231, Pages: 13, Words: 11789
                Categories
                Psychiatry
                Review

                Clinical Psychology & Psychiatry
                testosterone,cortisol,emotion,affect,reward,self-regulation,sex differences

                Comments

                Comment on this article