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      Addressing and Overcoming Barriers to E-Cigarette Use for Smoking Cessation in Pregnancy: A Qualitative Study

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          Abstract

          E-cigarettes may have a role in supporting pregnant women who would otherwise smoke to stop smoking. The study aimed to understand pregnant women’s vaping experiences, in particular how vaping to stop smoking is facilitated and how barriers to this are overcome. We conducted semi structured telephone interviews ( n = 15) with pregnant or postpartum women who vaped during pregnancy, either exclusively ( n = 10) or dual-used ( n = 5) (smoked and vaped). Thematic analysis was used to analyse the interviews. Two themes emerged. First, ‘facilitating beliefs’: inherent beliefs that helped women overcome barriers to vaping. These included understanding the relative safety of vaping and economic gains compared with smoking and pregnancy being a motivator to stop smoking. Second, ‘becoming a confident vaper’: accumulating sufficient skill and confidence to comfortably vape. This included experimentation with e-cigarettes to ensure nicotine dependence and sensory needs were met. Seeking social support and employing strategies to address social stigma were also important. Positive beliefs about vaping and becoming proficient at vaping were viewed as ways to overcome barriers to vaping. The theoretical domain framework informed intervention recommendations to assist pregnant smokers who have tried but cannot stop smoking to switch to vaping.

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          Most cited references34

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          Nicotine, Carcinogen, and Toxin Exposure in Long-Term E-Cigarette and Nicotine Replacement Therapy Users : A Cross-sectional Study

          Given the rapid increase in the popularity of e-cigarettes and the paucity of associated longitudinal health-related data, the need to assess the potential risks of long-term use is essential.
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            Cardiovascular toxicity of nicotine: Implications for electronic cigarette use.

            The cardiovascular safety of nicotine is an important question in the current debate on the benefits vs. risks of electronic cigarettes and related public health policy. Nicotine exerts pharmacologic effects that could contribute to acute cardiovascular events and accelerated atherogenesis experienced by cigarette smokers. Studies of nicotine medications and smokeless tobacco indicate that the risks of nicotine without tobacco combustion products (cigarette smoke) are low compared to cigarette smoking, but are still of concern in people with cardiovascular disease. Electronic cigarettes deliver nicotine without combustion of tobacco and appear to pose low-cardiovascular risk, at least with short-term use, in healthy users.
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              Effects of Nicotine During Pregnancy: Human and Experimental Evidence

              Prenatal exposure to tobacco smoke is a major risk factor for the newborn, increasing morbidity and even mortality in the neonatal period but also beyond. As nicotine addiction is the factor preventing many women from smoking cessation during pregnancy, nicotine replacement therapy (NRT) has been suggested as a better alternative for the fetus. However, the safety of NRT has not been well documented, and animal studies have in fact pointed to nicotine per se as being responsible for a multitude of these detrimental effects. Nicotine interacts with endogenous acetylcholine receptors in the brain and lung, and exposure during development interferes with normal neurotransmitter function, thus evoking neurodevelopmental abnormalities by disrupting the timing of neurotrophic actions. As exposure to pure nicotine is quite uncommon in pregnant women, very little human data exist aside from the vast literature on prenatal exposure to tobacco smoke. The current review discusses recent findings in humans on effects on the newborn of prenatal exposure to pure nicotine and non-smoke tobacco. It also reviews the neuropharmacological properties of nicotine during gestation and findings in animal experiments that offer explanations on a cellular level for the pathogenesis of such prenatal drug exposure. It is concluded that as findings indicate that functional nAChRs are present very early in neuronal development, and that activation at this stage leads to apoptosis and mitotic abnormalities, a total abstinence from all forms of nicotine should be advised to pregnant women for the entirety of gestation.
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                Author and article information

                Journal
                Int J Environ Res Public Health
                Int J Environ Res Public Health
                ijerph
                International Journal of Environmental Research and Public Health
                MDPI
                1661-7827
                1660-4601
                04 July 2020
                July 2020
                : 17
                : 13
                : 4823
                Affiliations
                [1 ]Division of Primary Care, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK; sue.cooper@ 123456nottingham.ac.uk (S.C.); sophie.orton@ 123456nottingham.ac.uk (S.O.); Tim.coleman@ 123456nottingham.ac.uk (T.C.); kasia.campbell@ 123456nottingham.ac.uk (K.A.C.)
                [2 ]Population Health Research Institute, St George’s, University of London, London SW17 0RE, UK; mussher@ 123456sgul.ac.uk
                [3 ]Institute for Social Marketing and Health, University of Stirling, Stirling FK9 4LA, UK
                Author notes
                [* ]Correspondence: katharine.bowker@ 123456nottingham.ac.uk ; Tel.: +44-0115-748-4040
                Author information
                https://orcid.org/0000-0002-1994-6395
                https://orcid.org/0000-0002-8577-216X
                https://orcid.org/0000-0002-7303-4805
                https://orcid.org/0000-0001-7453-9138
                Article
                ijerph-17-04823
                10.3390/ijerph17134823
                7369696
                32635510
                d6158fef-c30c-477c-aa18-fa1a941183d2
                © 2020 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 30 May 2020
                : 01 July 2020
                Categories
                Article

                Public health
                pregnancy,electronic cigarettes,vaping,smoking cessation,barriers
                Public health
                pregnancy, electronic cigarettes, vaping, smoking cessation, barriers

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