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      Thoracic imaging tests for the diagnosis of COVID-19

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          Abstract

          <p class="first" id="d2491506e359">The diagnosis of infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents major challenges. Reverse transcriptase polymerase chain reaction (RT-PCR) testing is used to diagnose a current infection, but its utility as a reference standard is constrained by sampling errors, limited sensitivity (71% to 98%), and dependence on the timing of specimen collection. Chest imaging tests are being used in the diagnosis of COVID-19 disease, or when RT-PCR testing is unavailable. </p>

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          Author and article information

          Journal
          146518
          Cochrane Database of Systematic Reviews
          Wiley
          14651858
          September 30 2020
          Affiliations
          [1 ]Department of Radiology; University of Ottawa; Ottawa Canada
          [2 ]Faculty of Health Sciences; Queen's University; Kingston Canada
          [3 ]Department of Clinical Epidemiology, Biostatistics and Bioinformatics; Amsterdam University Medical Centers, University of Amsterdam; Amsterdam Netherlands
          [4 ]Cochrane Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University; Utrecht Netherlands
          [5 ]Department of Radiology; McMaster University; Hamilton Canada
          [6 ]Department of Medicine; University of Ottawa; Ottawa Canada
          [7 ]Department of Radiology; Royal Free London NHS Trust; London UK
          [8 ]Department of Medical Imaging; The Ottawa Hospital; Ottawa Canada
          [9 ]Medical Library; Amsterdam UMC, University of Amsterdam, Amsterdam Public Health; Amsterdam Netherlands
          [10 ]Test Evaluation Research Group, Institute of Applied Health Research; University of Birmingham; Birmingham UK
          [11 ]NIHR Birmingham Biomedical Research Centre; University Hospitals Birmingham NHS Foundation Trust and University of Birmingham; Birmingham UK
          [12 ]Department of Respiratory Medicine; Amsterdam UMC, University of Amsterdam; Amsterdam Netherlands
          [13 ]Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé); Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS), Inserm UMR1153, Paris Descartes University; Paris France
          [14 ]NIHR Diagnostic Evidence Cooperative; University of Oxford; Oxford UK
          [15 ]Institute of Infection, Veterinary, and Ecological Sciences; University of Liverpool; Liverpool UK
          [16 ]Julius Center for Health Sciences and Primary Care; University Medical Center Utrecht; Utrehct Netherlands
          Article
          10.1002/14651858.CD013639.pub2
          32997361
          d6294c30-0586-430d-b9c4-f0498fce1f4f
          © 2020
          History

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