13
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Cell biology and immunology of Listeria monocytogenes infections: novel insights.

      Immunological Reviews

      Humans, Immune Evasion, Listeria monocytogenes, growth & development, immunology, Listeriosis, physiopathology, Microbial Interactions, Models, Biological

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Listeria monocytogenes is an intracellular bacterium responsible for a disease characterized by several clinical features, such as septicemia, brain infection, abortion, and perinatal infection. These clinical features are attributed to its amazing capacity to cross several barriers in susceptible hosts. Intracellular infection is a consequence of the bacterium's capacity to enter a wide variety of mammalian cells, to not only survive but also replicate therein, and to its faculty to spread from one cell to the next, thereby escaping the humoral immune response. Here, we review both the well-established and the newly discovered strategies used by this bacterium to achieve this intracellular lifestyle while escaping from the host innate immune response. More than ever, Listeria appears as a model system and a reference in infection biology. © 2011 John Wiley & Sons A/S.

          Related collections

          Author and article information

          Journal
          21349093
          10.1111/j.1600-065X.2010.00993.x

          Comments

          Comment on this article